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A Systematic Prediction of Drug-Target Interactions Using Molecular Fingerprints and Protein Sequences 期刊论文
CURRENT PROTEIN & PEPTIDE SCIENCE, 2018, 卷号: 19, 期号: 5, 页码: 468-478
Authors:  Huang, YA (Huang, Yu-An);  You, ZH (You, Zhu-Hong);  Chen, X (Chen, Xing)
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Drug-target Interactions  Pseudo Substitution Matrix Representation  Drug Substructure Fingerprint  Extremely Randomized Trees  Computational Model  
Constructing prediction models from expression profiles for large scale lncRNA-miRNA interaction profiling 期刊论文
BIOINFORMATICS, 2018, 卷号: 34, 期号: 5, 页码: 812-819
Authors:  Huang, YA (Huang, Yu-An);  Chan, KCC (Chan, Keith C. C.);  You, ZH (You, Zhu-Hong);  Huang, YA
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An ensemble approach for large-scale identification of protein-protein interactions using the alignments of multiple sequences 期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 3, 页码: 5149-5159
Authors:  Wang, L (Wang, Lei);  You, ZH (You, Zhu-Hong);  Chen, X (Chen, Xing);  Li, JQ (Li, Jian-Qiang);  Yan, X (Yan, Xin);  Zhang, W (Zhang, Wei);  Huang, YA (Huang, Yu-An)
Adobe PDF(2107Kb)  |  Favorite  |  View/Download:68/0  |  Submit date:2017/03/17
Disease  Position-specific Scoring Matrix  Multiple Sequences Alignments  Cancer  
Detection of Interactions between Proteins by Using Legendre Moments Descriptor to Extract Discriminatory Information Embedded in PSSM 期刊论文
MOLECULES, 2017, 卷号: 22, 期号: 8, 页码: 1-13
Authors:  Wang, YB (Wang, Yan-Bin);  You, ZH (You, Zhu-Hong);  Li, LP (Li, Li-Ping);  Huang, YA (Huang, Yu-An);  Yi, HC (Yi, Hai-Cheng)
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Protein-protein Interactions  Legendre Moments  Position Specific Scoring Matrix  Probabilistic Classification Vector Machine  
EPMDA: an expression-profile based computational model for microRNA-disease association prediction 期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 50, 页码: 87033-87043
Authors:  Huang, YA (Huang, Yu-An);  You, ZH (You, Zhu-Hong);  Li, LP (Li, Li-Ping);  Huang, ZA (Huang, Zhi-An);  Xiang, LX (Xiang, Lu-Xuan);  Li, XF (Li, Xiao-Fang);  Lv, LT (Lv, Lin-Tao)
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Disease  Microrna  Expression Profile  Biomarker  
Accurate prediction of protein-protein interactions by integrating potential evolutionary information embedded in PSSM profile and discriminative vector machine classifier 期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 14, 页码: 23638-23649
Authors:  Li, ZW (Li, Zheng-Wei);  You, ZH (You, Zhu-Hong);  Chen, X (Chen, Xing);  Li, LP (Li, Li-Ping);  Huang, DS (Huang, De-Shuang);  Yan, GY (Yan, Gui-Ying);  Nie, R (Nie, Ru);  Huang, YA (Huang, Yu-An)
Adobe PDF(3973Kb)  |  Favorite  |  View/Download:63/0  |  Submit date:2017/05/17
Disease  Position-specific Scoring Matrix  Weber Local Descriptor  Cancer  Protein-protein Interactions  
A novel approach based on KATZ measure to predict associations of human microbiota with non-infectious diseases 期刊论文
BIOINFORMATICS, 2017, 卷号: 33, 期号: 5, 页码: 733-739
Authors:  Chen, X (Chen, Xing);  Huang, YA (Huang, Yu-An);  You, ZH (You, Zhu-Hong);  Yan, GY (Yan, Gui-Ying);  Wang, XS (Wang, Xue-Song)
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Construction of reliable protein-protein interaction networks using weighted sparse representation based classifier with pseudo substitution matrix representation features 期刊论文
NEUROCOMPUTING, 2016, 卷号: 218, 期号: 12, 页码: 131-138
Authors:  Huang, YA (Huang, Yu-An);  You, ZH (You, Zhu-Hong);  Li, X (Li, Xiao);  Chen, X (Chen, Xing);  Hu, PW (Hu, Pengwei);  Li, S (Li, Shuai);  Luo, X (Luo, Xin)
Adobe PDF(799Kb)  |  Favorite  |  View/Download:93/0  |  Submit date:2016/12/07
Protein-protein Interaction Networks  Protein Sequence  Substitution Matrix Representation  Weighted Sparse Representation  
Improved protein-protein interactions prediction via weighted sparse representation model combining continuous wavelet descriptor and PseAA composition 期刊论文
BMC SYSTEMS BIOLOGY, 2016, 卷号: 10, 期号: 增刊: 4, 页码: 486-494
Authors:  Huang, YA (Huang, Yu-An);  You, ZH (You, Zhu-Hong);  Chen, X (Chen, Xing);  Yan, GY (Yan, Gui-Ying)
Adobe PDF(1228Kb)  |  Favorite  |  View/Download:28/0  |  Submit date:2018/01/23
Protein-protein Interactions  Protein Sequence  Continuous Wavelet Transform  Sparse Representation Based Classifier