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Targeting the Next Generation of Deep-Ultraviolet Nonlinear Optical Materials: Expanding from Borates to Borate Fluorides to Fluorooxoborates 期刊论文
ACCOUNTS OF CHEMICAL RESEARCH, 2019, 卷号: 52, 期号: 3, 页码: 791-801
Authors:  Mutailipu, M (Mutailipu, Miriding)[ 1,2,3 ];  Zhang, M (Zhang, Min)[ 1,2,3 ];  Yang, ZH (Yang, Zhihua)[ 1,2,3 ];  Pan, SL (Pan, Shilie)[ 1,2,3 ]
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Pharmacokinetics-Driven Optimization of 4(3H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 10, 页码: 4979-4990
Authors:  Wang, Z (Wang, Zhen)[ 1 ];  Jiang, XR (Jiang, Xiangrui)[ 1 ];  Zhang, XL (Zhang, Xianglei)[ 1,2 ];  Tian, GH (Tian, Guanghui)[ 3 ];  Yang, RL (Yang, Rulei)[ 3 ];  Wu, JZ (Wu, Jianzhong)[ 3 ];  Zou, XL (Zou, Xiaoli)[ 3 ];  Liu, Z (Liu, Zheng)[ 4 ];  Yang, XJ (Yang, Xiaojun)[ 4 ];  Wu, CH (Wu, Chunhui)[ 4 ];  Shi, J (Shi, Jing)[ 4 ];  Li, JF (Li, Jianfeng)[ 1 ];  Suo, J (Suo, Jin)[ 1 ];  Wang, Y (Wang, Yu)[ 1 ];  Zhang, RX (Zhang, Rongxia)[ 1 ];  Xu, ZJ (Xu, Zhijian)[ 1 ];  Gong, XD (Gong, Xudong)[ 1,5 ];  He, Y (He, Yang)[ 1 ];  Zhu, WL (Zhu, Weiliang)[ 1,2 ];  Aisa, HA (Aisa, Haji Akber)[ 5 ];  Jiang, HL (Jiang, Hualiang)[ 1,2 ];  Xu, YC (Xu, Yechun)[ 1,2 ];  Shen, JS (Shen, Jingshan)[ 1,2
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Sequence-based Prediction of Protein-Protein Interactions Using Gray Wolf Optimizer-Based Relevance Vector Machine 期刊论文
EVOLUTIONARY BIOINFORMATICS, 2019, 卷号: 15, 期号: 5, 页码: 1-10
Authors:  An, JY (An, Ji-Yong)[ 1,2 ];  You, ZH (You, Zhu-Hong)[ 3 ];  Zhou, Y (Zhou, Yong)[ 1,2 ];  Wang, DF (Wang, Da-Fu)[ 1,2 ]
Adobe PDF(462Kb)  |  Favorite  |  View/Download:33/0  |  Submit date:2019/06/28
RVM  gray wolf optimizer  BIG  PSSM  
Standard and figure-of-merit for quantifying the performance of pyroelectricnanogenerators 期刊论文
NANO ENERGY, 2019, 卷号: 55, 期号: 1, 页码: 534-540
Authors:  Zhang, KW (Zhang, Kewei)[ 1 ];  Wang, YH (Wang, Yuanhao)[ 2 ];  Wang, ZL (Wang, Zhong Lin)[ 1,3,4,5 ];  Yang, Y (Yang, Ya)[ 1,3,4 ]
Adobe PDF(2415Kb)  |  Favorite  |  View/Download:49/0  |  Submit date:2019/01/16
Pyroelectric nanogenerators  Figure-of-merits  Heat energy  Charge-voltage cycle  
复方金鹳草降糖有效部位的制备工艺及药理作用研究 学位论文
博士, 北京: 中国科学院大学, 2018
Authors:  萨拉麦提·艾迪热斯
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复方金鹳草降糖有效部位  糖尿病  胰岛素抵抗  内质网应激  
查尔酮衍生物和呋喃香豆素衍生物的设计、合成及促黑素合成机制研究 学位论文
博士, 北京: 中国科学院大学, 2018
Authors:  尹丽
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白癜风  黑色素合成  查尔酮和呋喃香豆素衍生物  Wnt/β-catenin 信号 通路  Pka/p38 Mapk 信号通路  
噻吩并[2,3-d]嘧啶-4(3H)-酮衍生物的合成及其活性研究 学位论文
硕士, 北京: 中国科学院大学, 2018
Authors:  刘飞泽
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噻吩并嘧啶类衍生物  合成  抗肿瘤活性  抗流感活性  
伊贝母多糖的分离分析及其生物活性研究 学位论文
硕士, 北京: 中国科学院大学, 2018
Authors:  阿衣吐逊·阿布都外力
Adobe PDF(3446Kb)  |  Favorite  |  View/Download:61/0  |  Submit date:2018/07/06
伊贝母  多糖  分离纯化  结构分析  生物活性  
核苷类抗丙型肝炎病毒和三氮唑类抗真菌化合物的合成研究 学位论文
博士, 北京: 中国科学院大学, 2018
Authors:  朱富强
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丙型肝炎病毒  核糖核苷  磷酸酯前药  三氮唑类抗真菌药物  艾氟康 唑  绿色合成路线与工艺  
噻吩[2,3-d]嘧啶酮衍生物的合成及其生物活性研究 学位论文
博士, 北京: 中国科学院大学, 2018
Authors:  聂礼飞
Adobe PDF(5171Kb)  |  Favorite  |  View/Download:81/0  |  Submit date:2018/07/06
抗肿瘤  噻吩[2  苯磺酰  3-d]嘧啶酮  黑素生成  抗菌