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Pharmacophore-based drug design for the identification of novel butyrylcholinesterase inhibitors against Alzheimer's disease 期刊论文
PHYTOMEDICINE, 2019, 卷号: 54, 期号: 2, 页码: 278-290
Authors:  Jiang, YY (Jiang, Yingying)[ 2 ];  Gao, HW (Gao, Hongwei)[ 1,2 ]
Adobe PDF(10366Kb)  |  Favorite  |  View/Download:22/1  |  Submit date:2019/03/19
Alzheimer's disease (AD)  Butyrylcholinesterase (BChE)  Flavonoids  Pharmacophore models  Molecular docking  De novo evolution  
A new fatty acid ester from Nigella sativa var. hispidula Boiss showing potent anti-protein tyrosine phosphatase 1B activity. 期刊论文
Natural product research, 2019, 卷号: 33, 期号: 4, 页码: 472-476
Authors:  Liu, XX (Liu, Xixi)[ 1,2,3 ];  Aisa, HA (Aisa, Haji Akber)[ 1,2 ];  Xin, XL (Xin, Xuelei)[ 1,2 ]
Adobe PDF(899Kb)  |  Favorite  |  View/Download:26/0  |  Submit date:2018/07/20
Nigella sativa var  hispidula  fatty acid ester  phenolic compounds  anti-PTP1B activity  
In Silico Prediction of Small Molecule-miRNA Associations Based on the HeteSim Algorithm 期刊论文
MOLECULAR THERAPY-NUCLEIC ACIDS, 2019, 卷号: 14, 期号: 3, 页码: 274-286
Authors:  Qu, J (Qu, Jia)[ 1 ];  Chen, X (Chen, Xing)[ 1 ];  Sun, YZ (Sun, Ya-Zhou)[ 2 ];  Zhao, Y (Zhao, Yan)[ 1 ];  Cai, SB (Cai, Shu-Bin)[ 2 ];  Ming, Z (Ming, Zhong)[ 2 ];  You, ZH (You, Zhu-Hong)[ 3 ];  Li, JQ (Li, Jian-Qiang)[ 2 ]
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LMTRDA: Using logistic model tree to predict MiRNA-disease associations by fusing multi-source information of sequences and similarities 期刊论文
PLOS COMPUTATIONAL BIOLOGY, 2019, 卷号: 15, 期号: 3, 页码: 1-18
Authors:  Wang, L (Wang, Lei)[ 1 ];  You, ZH (You, Zhu-Hong)[ 1 ];  Chen, X (Chen, Xing)[ 2 ];  Li, YM (Li, Yang-Ming)[ 3 ];  Dong, YN (Dong, Ya-Nan)[ 4 ];  Li, LP (Li, Li-Ping)[ 1 ];  Zheng, K (Zheng, Kai)[ 1 ]
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Prediction of Self-Interacting Proteins from Protein Sequence Information Based on Random Projection Model and Fast Fourier Transform 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, 卷号: 20, 期号: 4, 页码: 1-15
Authors:  Chen, ZH (Chen, Zhan-Heng)[ 1,2 ];  You, ZH (You, Zhu-Hong)[ 1,2 ];  Li, LP (Li, Li-Ping)[ 1 ];  Wang, YB (Wang, Yan-Bin)[ 1 ];  Wong, L (Wong, Leon)[ 1,2 ];  Yi, HC (Yi, Hai-Cheng)[ 1,2 ]
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self-interacting proteins  position-specific scoring matrix  fast Fourier transform  random projection  
Triterpenoids and triterpenoid saponins from Dipsacus asper and their cytotoxic and antibacterial activities 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 162, 期号: 6, 页码: 241-249
Authors:  Yu, JH (Yu, Jin-Hai)[ 1 ];  Yu, ZP (Yu, Zhi-Pu)[ 1,2 ];  Wang, YY (Wang, Yin-Yin)[ 1 ];  Bao, J (Bao, Jie)[ 1 ];  Zhu, KK (Zhu, Kong-Kai)[ 1 ];  Yuan, T (Yuan, Tao)[ 3 ];  Zhang, H (Zhang, Hua)[ 1 ]
Adobe PDF(1200Kb)  |  Favorite  |  View/Download:17/0  |  Submit date:2019/06/21
Dipsacus asper  Caprifoliaceae  Triterpenoid  Triterpenoid saponin  Cytotoxicity  
瘤果黑种草籽中降糖成分的研究 学位论文
, 北京: 中国科学院大学, 2018
Authors:  刘喜喜
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瘤果黑种草籽  生物碱  异苯并呋喃酮  蛋白酪氨酸磷酸酶1b抑制剂  醛糖还原酶抑制剂  
复方金鹳草降糖有效部位的制备工艺及药理作用研究 学位论文
, 北京: 中国科学院大学, 2018
Authors:  萨拉麦提·艾迪热斯
Adobe PDF(4606Kb)  |  Favorite  |  View/Download:59/0  |  Submit date:2018/07/06
复方金鹳草降糖有效部位  糖尿病  胰岛素抵抗  内质网应激  
菊苣酸和绿原酸的分子印迹快速分离研究 学位论文
, 北京: 中国科学院大学, 2018
Authors:  孙亚坤
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分子印迹聚合物  菊苣酸  绿原酸  离子液体  在线固相萃取  
伊贝母多糖的分离分析及其生物活性研究 学位论文
, 北京: 中国科学院大学, 2018
Authors:  阿衣吐逊·阿布都外力
Adobe PDF(3446Kb)  |  Favorite  |  View/Download:51/0  |  Submit date:2018/07/06
伊贝母  多糖  分离纯化  结构分析  生物活性