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Pharmacokinetics-Driven Optimization of 4(3H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 10, 页码: 4979-4990
Authors:  Wang, Z (Wang, Zhen)[ 1 ];  Jiang, XR (Jiang, Xiangrui)[ 1 ];  Zhang, XL (Zhang, Xianglei)[ 1,2 ];  Tian, GH (Tian, Guanghui)[ 3 ];  Yang, RL (Yang, Rulei)[ 3 ];  Wu, JZ (Wu, Jianzhong)[ 3 ];  Zou, XL (Zou, Xiaoli)[ 3 ];  Liu, Z (Liu, Zheng)[ 4 ];  Yang, XJ (Yang, Xiaojun)[ 4 ];  Wu, CH (Wu, Chunhui)[ 4 ];  Shi, J (Shi, Jing)[ 4 ];  Li, JF (Li, Jianfeng)[ 1 ];  Suo, J (Suo, Jin)[ 1 ];  Wang, Y (Wang, Yu)[ 1 ];  Zhang, RX (Zhang, Rongxia)[ 1 ];  Xu, ZJ (Xu, Zhijian)[ 1 ];  Gong, XD (Gong, Xudong)[ 1,5 ];  He, Y (He, Yang)[ 1 ];  Zhu, WL (Zhu, Weiliang)[ 1,2 ];  Aisa, HA (Aisa, Haji Akber)[ 5 ];  Jiang, HL (Jiang, Hualiang)[ 1,2 ];  Xu, YC (Xu, Yechun)[ 1,2 ];  Shen, JS (Shen, Jingshan)[ 1,2
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新疆四种动物骨髓蛋白与油脂的分离分析及其应用研究 学位论文
博士, 北京: 中国科学院大学, 2018
Authors:  帕尔哈提·柔孜
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动物骨髓  蛋白与多肽  液质联用色谱  营养成分  生物活性  
PHENOLIC COMPOUNDS FROM LEAVES OF Nitraria sibirica 期刊论文
CHEMISTRY OF NATURAL COMPOUNDS, 2018, 卷号: 54, 期号: 5, 页码: 987-989
Authors:  Turghun, C (Turghun, Ch)[ 1,2,3 ];  Bakri, M (Bakri, M.)[ 1,2 ];  Zou, GA (Zou, G. A.)[ 1,2 ];  Bobakulov, KM (Bobakulov, Kh M.)[ 4 ];  Aisa, HA (Aisa, H. A.)[ 1,2 ]
Adobe PDF(141Kb)  |  Favorite  |  View/Download:35/0  |  Submit date:2018/10/19
粗毛褐孔菌和石榴花化学成分及其生物活性研究 学位论文
硕士, 北京: 中国科学院大学, 2017
Authors:  任青
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粗毛褐孔菌  石榴花  多酚类  羊毛甾烷型三萜  抗白癜风  
PFP alleviates nonalcoholic steatohepatitis fatty liver in both Apo E(-/-)mice and Changliver cell[S] 期刊论文
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH, 2017, 卷号: 9, 期号: 6, 页码: 3073-3083
Authors:  Yan, D (Yan, Dong);  Wei, YY (Wei, Yuan-Yuan);  Li, XM (Li, Xiu-Mei);  Sun, XC (Sun, Xiu-Chao);  Wang, Z (Wang, Zhong);  Aisa, HA (Aisa, Haji Akber);  Aisa, HA
Adobe PDF(1358Kb)  |  Favorite  |  View/Download:20/0  |  Submit date:2018/01/09
Pfp (Pomegranate Flower Polyphone)  Nonalcoholic Fatty Liver Disease  Apo E-/- Mice  
PBMDA: A novel and effective path-based computational model for miRNA-disease association prediction 期刊论文
PLOS COMPUTATIONAL BIOLOGY, 2017, 卷号: 13, 期号: 3, 页码: 1-22
Authors:  You, ZH (You, Zhu-Hong);  Huang, ZA (Huang, Zhi-An);  Zhu, ZX (Zhu, Zexuan);  Yan, GY (Yan, Gui-Ying);  Li, ZW (Li, Zheng-Wei);  Wen, ZK (Wen, Zhenkun);  Chen, X (Chen, Xing)
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矮膜苞芹水提物对肾性高血压大鼠的降血压作用研究 期刊论文
新疆医科大学学报, 2017, 卷号: 40, 期号: 5, 页码: 638-641+645
Authors:  朱金芳;  张雪;  胡江兰;  兰卫;  朱慧敏;  刘洋
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矮膜苞芹  肾性高血压大鼠  降血压  机制  
Fabrication of highly efficient anodes based on structural and compositional modifications for electrochemical oxidation of recalcitrant pollutants 学位论文
博士, 北京: 中国科学院大学, 2016
Authors:  Sumreen Asim
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Fabrication  Highly Efficient Anodes  Electrochemical Oxidation  Recalcitrant Pollutants  
鹰嘴豆豆芽标准提取物对乳腺癌的干预及机制研究 学位论文
博士, 北京: 中国科学院大学, 2016
Authors:  陈花
Adobe PDF(8783Kb)  |  Favorite  |  View/Download:117/0  |  Submit date:2016/09/27
鹰嘴豆芽  异黄酮  线粒体依赖性细胞凋亡  乳腺癌  化学预防  
罗布麻和雪菊的化学成分及其生物活性研究 学位论文
博士, 北京: 中国科学院大学, 2016
Authors:  NURMIRZA BEGMATOV
Adobe PDF(4846Kb)  |  Favorite  |  View/Download:63/0  |  Submit date:2017/08/22
罗布麻  雪菊  分离纯化  结构鉴定  黄酮  查尔酮  生物活性筛选和评价