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噻吩并[2,3-d]嘧啶-4(3H)-酮衍生物的合成及其活性研究 学位论文
硕士, 北京: 中国科学院大学, 2018
Authors:  刘飞泽
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噻吩并嘧啶类衍生物  合成  抗肿瘤活性  抗流感活性  
对叶大戟二萜类成分逆转肿瘤多药耐药的研究 学位论文
博士, 北京: 中国科学院大学, 2018
Authors:  胡蕊
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对叶大戟  假白榄烷型大环二萜  肿瘤多药耐药逆转  P-gp蛋白调节剂  
噻吩[2,3-d]嘧啶酮衍生物的合成及其生物活性研究 学位论文
博士, 北京: 中国科学院大学, 2018
Authors:  聂礼飞
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抗肿瘤  噻吩[2  苯磺酰  3-d]嘧啶酮  黑素生成  抗菌  
计算机辅助药物设计在治疗阿尔兹海默症中的应用 学位论文
硕士, 北京: 中国科学院大学, 2018
Authors:  蒋迎迎
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阿尔兹海默症  乙酰胆碱酯酶  丁酰胆碱酯酶  分子对接  药效团模型  
ES2 enhances the efficacy of chemotherapeutic agents in ABCB1-overexpressing cancer cells in vitro and in vivo 期刊论文
PHARMACOLOGICAL RESEARCH, 2018, 卷号: 129, 期号: 3, 页码: 388-399
Authors:  Fang, YF (Fang, Yanfen);  Sun, JJ (Sun, Juanjuan);  Zhong, X (Zhong, Xing);  Hu, R (Hu, Rui);  Gao, J (Gao, Jie);  Duan, GF (Duan, Guanfu);  Ji, CG (Ji, Changge);  Chen, LJ (Chen, Lijuan);  Zhang, WL (Zhang, Wanli);  Miao, CX (Miao, Chunxiao);  Aisa, HA (Aisa, Haji Akber);  Zhang, XW (Zhang, Xiongwen)
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Mdr  Abcb1  Jatrophane Diterpenoid Ester  Chemotherapeutic Agents  
Predicting tyrosinase inhibition by 3D QSAR pharmacophore models and designing potential tyrosinase inhibitors from Traditional Chinese medicine database 期刊论文
PHYTOMEDICINE, 2018, 卷号: 38, 期号: 1, 页码: 145-157
Authors:  Gao, HW (Gao, Hongwei)
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Tyrosinase  Inhibitors  Tcm  Pharmacophore Models  Docking  
Pharmacophore-based drug design for potential AChE inhibitors from Traditional Chinese Medicine Database 期刊论文
BIOORGANIC CHEMISTRY, 2018, 卷号: 76, 期号: 2, 页码: 400-414
Authors:  Jiang, YY (Jiang, Yingying);  Gao, HW (Gao, Hongwei);  Gao, HW
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Ad  Ache  Flavonoids  Tcm  Pharmacophore Models  Docking  
Diversity-oriented synthesis of amide derivatives of tricyclic thieno[2,3-d]pyrimidin-4(3H)-ones and evaluation of their influence on melanin synthesis in murine B16 cells 期刊论文
HETEROCYCLIC COMMUNICATIONS, 2018, 卷号: 24, 期号: 1, 页码: 43-50
Authors:  Nie, LF (Nie, Li Fei);  Huang, GZ (Huang, Guozheng);  Bozorov, K (Bozorov, Khurshed);  Zhao, JY (Zhao, Jiangyu);  Niu, C (Niu, Chao);  Sagdullaev, SS (Sagdullaev, Shamansur S.);  Aisa, HA (Aisa, Haji A.)
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Melanin Synthesis  Murine B16 Cells  Vitiligo  Thieno[2  3-d]Pyrimidin-4(3h)-one  
Plant dipeptidyl peptidase-IV inhibitors as antidiabetic agents: a brief review 期刊论文
FUTURE MEDICINAL CHEMISTRY, 2018, 卷号: 10, 期号: 10, 页码: 1229-1239
Authors:  Turdu, G (Turdu, Gulmira);  Gao, HW (Gao, Hongwei);  Jiang, YY (Jiang, Yingying);  Kabas, M (Kabas, Madina)
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Antidiabetic  Dipeptidyl Peptidase Iv  Dpp-iv Inhibitors  Type 2 Diabetes  
A Systematic Prediction of Drug-Target Interactions Using Molecular Fingerprints and Protein Sequences 期刊论文
CURRENT PROTEIN & PEPTIDE SCIENCE, 2018, 卷号: 19, 期号: 5, 页码: 468-478
Authors:  Huang, YA (Huang, Yu-An);  You, ZH (You, Zhu-Hong);  Chen, X (Chen, Xing)
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Drug-target Interactions  Pseudo Substitution Matrix Representation  Drug Substructure Fingerprint  Extremely Randomized Trees  Computational Model