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Pharmacophore-based drug design for the identification of novel butyrylcholinesterase inhibitors against Alzheimer's disease 期刊论文
PHYTOMEDICINE, 2019, 卷号: 54, 期号: 2, 页码: 278-290
Authors:  Jiang, YY (Jiang, Yingying)[ 2 ];  Gao, HW (Gao, Hongwei)[ 1,2 ]
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Alzheimer's disease (AD)  Butyrylcholinesterase (BChE)  Flavonoids  Pharmacophore models  Molecular docking  De novo evolution  
计算机辅助药物设计在治疗阿尔兹海默症中的应用 学位论文
硕士, 北京: 中国科学院大学, 2018
Authors:  蒋迎迎
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阿尔兹海默症  乙酰胆碱酯酶  丁酰胆碱酯酶  分子对接  药效团模型  
Predicting tyrosinase inhibition by 3D QSAR pharmacophore models and designing potential tyrosinase inhibitors from Traditional Chinese medicine database 期刊论文
PHYTOMEDICINE, 2018, 卷号: 38, 期号: 1, 页码: 145-157
Authors:  Gao, HW (Gao, Hongwei)
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Tyrosinase  Inhibitors  Tcm  Pharmacophore Models  Docking  
Pharmacophore-based drug design for potential AChE inhibitors from Traditional Chinese Medicine Database 期刊论文
BIOORGANIC CHEMISTRY, 2018, 卷号: 76, 期号: 2, 页码: 400-414
Authors:  Jiang, YY (Jiang, Yingying);  Gao, HW (Gao, Hongwei);  Gao, HW
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Ad  Ache  Flavonoids  Tcm  Pharmacophore Models  Docking  
Accurate Prediction of ncRNA-Protein Interactions From the Integration of Sequence and Evolutionary Information 期刊论文
FRONTIERS IN GENETICS, 2018, 卷号: 9, 期号: 10, 页码: 1-9
Authors:  Zhan, ZH (Zhan, Zhao-Hui)[ 1 ];  You, ZH (You, Zhu-Hong)[ 2 ];  Li, LP (Li, Li-Ping)[ 2 ];  Zhou, Y (Zhou, Yong)[ 1 ];  Yi, HC (Yi, Hai-Cheng)[ 2 ]
Adobe PDF(1220Kb)  |  Favorite  |  View/Download:24/0  |  Submit date:2018/10/19
Ncrna-protein Interactions  Pssm  Lightgbm  Pseudo-zernike Moments  K-mers  
三种维药经典药材生物碱类成分及其生物活性研究 学位论文
博士, 北京: 中国科学院大学, 2017
Authors:  陈其宾
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阿纳其根  天山堇菜  瘤果黑种草籽  生物碱  生物合成途径  
Highly Efficient Framework for Predicting Interactions Between Proteins 期刊论文
IEEE TRANSACTIONS ON CYBERNETICS, 2017, 卷号: 47, 期号: 3, 页码: 731-743
Authors:  You, ZH (You, Zhu-Hong);  Zhou, MC (Zhou, MengChu);  Luo, X (Luo, Xin);  Li, S (Li, Shuai)
Adobe PDF(3031Kb)  |  Favorite  |  View/Download:69/0  |  Submit date:2017/03/23
Big Data  Feature Extraction  Kernel Extreme Learning Machine (K-elm)  Low-rank Approximation (Lra)  Protein-protein Interactions (Ppis)  Support Vector Machine (Svm)  
Next-generation sequencing-based molecular diagnosis of 12 inherited retinal disease probands of Uyghur ethnicity 期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6, 期号: 2, 页码: 1-8
Authors:  Tajiguli, A (Tajiguli, Abulikemu);  Xu, MC (Xu, Mingchu);  Fu, Q (Fu, Qing);  Yiming, R (Yiming, Rouzimaimaiti);  Wang, KQ (Wang, Keqing);  Li, YM (Li, Yumei);  Eblimit, A (Eblimit, Aiden);  Sui, RF (Sui, Ruifang);  Chen, R (Chen, Rui);  Aisa, HA (Aisa, Haji Akber)
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有机介质中脂肪酶催化合成亚麻酸甘油酯 期刊论文
生物技术, 2006, 卷号: 16, 期号: 4, 页码: 47-49
Authors:  夏木西卡玛尔;  吾满江·艾力;  孙燕;  甘争艳;  刘勇;  张永学
Adobe PDF(148Kb)  |  Favorite  |  View/Download:150/10  |  Submit date:2012/11/29
脂肪酶  亚麻酸甘油酯  有机溶剂  酯化反应