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查尔酮衍生物和呋喃香豆素衍生物的设计、合成及促黑素合成机制研究 学位论文
博士, 北京: 中国科学院大学, 2018
Authors:  尹丽
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白癜风  黑色素合成  查尔酮和呋喃香豆素衍生物  Wnt/β-catenin 信号 通路  Pka/p38 Mapk 信号通路  
香豆素类衍生物合成及其抗白癜风活性和抗菌活性研究 学位论文
博士, 北京: 中国科学院大学, 2018
Authors:  庞广宪
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香豆素衍生物  补骨脂素  抗白癜风  黑色素生成  抗菌活性  
计算机辅助药物设计在治疗阿尔兹海默症中的应用 学位论文
硕士, 北京: 中国科学院大学, 2018
Authors:  蒋迎迎
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阿尔兹海默症  乙酰胆碱酯酶  丁酰胆碱酯酶  分子对接  药效团模型  
Predicting tyrosinase inhibition by 3D QSAR pharmacophore models and designing potential tyrosinase inhibitors from Traditional Chinese medicine database 期刊论文
PHYTOMEDICINE, 2018, 卷号: 38, 期号: 1, 页码: 145-157
Authors:  Gao, HW (Gao, Hongwei)
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Tyrosinase  Inhibitors  Tcm  Pharmacophore Models  Docking  
Pharmacophore-based drug design for potential AChE inhibitors from Traditional Chinese Medicine Database 期刊论文
BIOORGANIC CHEMISTRY, 2018, 卷号: 76, 期号: 2, 页码: 400-414
Authors:  Jiang, YY (Jiang, Yingying);  Gao, HW (Gao, Hongwei);  Gao, HW
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Ad  Ache  Flavonoids  Tcm  Pharmacophore Models  Docking  
A novel psoralen derivative-MPFC enhances melanogenesis via activation of p38 MAPK and PKA signaling pathways in B16 cells 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2018, 卷号: 41, 期号: 6, 页码: 3727-3735
Authors:  Yin, L (Yin, Li);  Pang, GX (Pang, Guangxian);  Niu, C (Niu, Chao);  Habasi, M (Habasi, Maidina);  Dou, J (Dou, Jun);  Aisa, HA (Aisa, Haji Akber)
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Melanogenesis  4-methyl-6-phenyl-2h-furo[3  Protein Kinase a Pathway  2-g]Chromen-2-one  P38 Mitogen-activated Protein Kinase  The Murine B16 Melanoma Cell  
Improving Prediction of Self-interacting Proteins Using Stacked Sparse Auto-Encoder with PSSM profiles 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2018, 卷号: 14, 期号: 8, 页码: 983-991
Authors:  Wang, YB (Wang, Yan-Bin);  You, ZH (You, Zhu-Hong);  Li, LP (Li, Li-Ping);  Huang, DS (Huang, De-Shuang);  Zhou, FF (Zhou, Feng-Feng);  Yang, S (Yang, Shan)
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Deep Learning  Zernike Moments  Probabilistic Classification Vector Machines  
Upregulation of Melanogenesis and Tyrosinase Activity: Potential Agents for Vitiligo 期刊论文
MOLECULES, 2017, 卷号: 22, 期号: 8, 页码: 1-28
Authors:  Niu, C (Niu, Chao);  Aisa, HA (Aisa, Haji A.)
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Melanogenesis  Tyrosinase Activity  Vitiligo  Plant Extracts  Natural Products  Synthesized Derivatives  Analogues  
Prediction of Drug-Target Interaction Networks from the Integration of Protein Sequences and Drug Chemical Structures 期刊论文
MOLECULES, 2017, 卷号: 22, 期号: 7, 页码: 1-13
Authors:  Meng, FR (Meng, Fan-Rong);  You, ZH (You, Zhu-Hong);  Chen, X (Chen, Xing);  Zhou, Y (Zhou, Yong);  An, JY (An, Ji-Yong)
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Dti  Rvm  Bigp  Pca  
Distributed Winner-Take-All in Dynamic Networks 期刊论文
IEEE TRANSACTIONS ON AUTOMATIC CONTROL, 2017, 卷号: 62, 期号: 2, 页码: 577-589
Authors:  Li, S (Li, Shuai);  Zhou, MC (Zhou, MengChu);  Luo, X (Luo, Xin);  You, ZH (You, Zhu-Hong)
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Competitive Control  Consensus  Cooperative Control  Distributed Control  Dynamic Networks  Networked Control System  Winner-take-all