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Prediction of Self-Interacting Proteins from Protein Sequence Information Based on Random Projection Model and Fast Fourier Transform 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, 卷号: 20, 期号: 4, 页码: 1-15
Authors:  Chen, ZH (Chen, Zhan-Heng)[ 1,2 ];  You, ZH (You, Zhu-Hong)[ 1,2 ];  Li, LP (Li, Li-Ping)[ 1 ];  Wang, YB (Wang, Yan-Bin)[ 1 ];  Wong, L (Wong, Leon)[ 1,2 ];  Yi, HC (Yi, Hai-Cheng)[ 1,2 ]
Adobe PDF(969Kb)  |  Favorite  |  View/Download:20/0  |  Submit date:2019/05/16
self-interacting proteins  position-specific scoring matrix  fast Fourier transform  random projection  
Sequence-based Prediction of Protein-Protein Interactions Using Gray Wolf Optimizer-Based Relevance Vector Machine 期刊论文
EVOLUTIONARY BIOINFORMATICS, 2019, 卷号: 15, 期号: 5, 页码: 1-10
Authors:  An, JY (An, Ji-Yong)[ 1,2 ];  You, ZH (You, Zhu-Hong)[ 3 ];  Zhou, Y (Zhou, Yong)[ 1,2 ];  Wang, DF (Wang, Da-Fu)[ 1,2 ]
Adobe PDF(462Kb)  |  Favorite  |  View/Download:33/0  |  Submit date:2019/06/28
RVM  gray wolf optimizer  BIG  PSSM  
基于深度学习的蛋白质相互作用预测研究 学位论文
硕士, 北京: 中国科学院大学, 2018
Authors:  王延斌
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蛋白质相互作用  深度学习  长短时记忆模型  位置特异性打分矩阵  
计算机辅助药物设计在治疗阿尔兹海默症中的应用 学位论文
硕士, 北京: 中国科学院大学, 2018
Authors:  蒋迎迎
Adobe PDF(4007Kb)  |  Favorite  |  View/Download:76/1  |  Submit date:2018/07/06
阿尔兹海默症  乙酰胆碱酯酶  丁酰胆碱酯酶  分子对接  药效团模型  
BNPMDA: Bipartite Network Projection for MiRNA-Disease Association prediction 期刊论文
BIOINFORMATICS, 2018, 卷号: 34, 期号: 18, 页码: 3178-3186
Authors:  Chen, X (Chen, Xing)[ 1 ];  Xie, D (Xie, Di)[ 2 ];  Wang, L (Wang, Lei)[ 1 ];  Zhao, Q (Zhao, Qi)[ 2,3 ];  You, ZH (You, Zhu-Hong)[ 4 ];  Liu, HS (Liu, Hongsheng)[ 3,5 ]
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Accurate Prediction of ncRNA-Protein Interactions From the Integration of Sequence and Evolutionary Information 期刊论文
FRONTIERS IN GENETICS, 2018, 卷号: 9, 期号: 10, 页码: 1-9
Authors:  Zhan, ZH (Zhan, Zhao-Hui)[ 1 ];  You, ZH (You, Zhu-Hong)[ 2 ];  Li, LP (Li, Li-Ping)[ 2 ];  Zhou, Y (Zhou, Yong)[ 1 ];  Yi, HC (Yi, Hai-Cheng)[ 2 ]
Adobe PDF(1220Kb)  |  Favorite  |  View/Download:24/0  |  Submit date:2018/10/19
Ncrna-protein Interactions  Pssm  Lightgbm  Pseudo-zernike Moments  K-mers  
Improving Prediction of Self-interacting Proteins Using Stacked Sparse Auto-Encoder with PSSM profiles 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2018, 卷号: 14, 期号: 8, 页码: 983-991
Authors:  Wang, YB (Wang, Yan-Bin);  You, ZH (You, Zhu-Hong);  Li, LP (Li, Li-Ping);  Huang, DS (Huang, De-Shuang);  Zhou, FF (Zhou, Feng-Feng);  Yang, S (Yang, Shan)
Adobe PDF(945Kb)  |  Favorite  |  View/Download:48/0  |  Submit date:2018/07/16
Deep Learning  Zernike Moments  Probabilistic Classification Vector Machines  
An improved efficient rotation forest algorithm to predict the interactions among proteins 期刊论文
SOFT COMPUTING, 2018, 卷号: 22, 期号: 10, 页码: 3373-3381
Authors:  Wang, L (Wang, Lei);  You, ZH (You, Zhu-Hong);  Xia, SX (Xia, Shi-Xiong);  Chen, X (Chen, Xing);  Yan, X (Yan, Xin);  Zhou, Y (Zhou, Yong);  Liu, F (Liu, Feng)
Adobe PDF(764Kb)  |  Favorite  |  View/Download:24/0  |  Submit date:2018/06/20
Rotation Forest  Ensemble Learning  Bioinformatics  Support Vector Machine  
A Systematic Prediction of Drug-Target Interactions Using Molecular Fingerprints and Protein Sequences 期刊论文
CURRENT PROTEIN & PEPTIDE SCIENCE, 2018, 卷号: 19, 期号: 5, 页码: 468-478
Authors:  Huang, YA (Huang, Yu-An);  You, ZH (You, Zhu-Hong);  Chen, X (Chen, Xing)
Adobe PDF(1888Kb)  |  Favorite  |  View/Download:23/0  |  Submit date:2018/05/15
Drug-target Interactions  Pseudo Substitution Matrix Representation  Drug Substructure Fingerprint  Extremely Randomized Trees  Computational Model  
PCLPred: A Bioinformatics Method for Predicting Protein-Protein Interactions by Combining Relevance Vector Machine Model with Low-Rank Matrix Approximation 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 卷号: 19, 期号: 4, 页码: 1-13
Authors:  Li, LP (Li, Li-Ping)[ 1 ];  Wang, YB (Wang, Yan-Bin)[ 2 ];  You, ZH (You, Zhu-Hong)[ 1 ];  Li, Y (Li, Yang)[ 1 ];  An, JY (An, Ji-Yong)[ 3 ]
Adobe PDF(2668Kb)  |  Favorite  |  View/Download:93/0  |  Submit date:2018/10/30
Protein-protein Interactions (Ppi)  Low Rank  Protein Sequence  Relevance Vector Machine (Rvm)  Evolutionary Information