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基于深度学习的蛋白质相互作用预测研究 学位论文
硕士, 北京: 中国科学院大学, 2018
Authors:  王延斌
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蛋白质相互作用  深度学习  长短时记忆模型  位置特异性打分矩阵  
An improved efficient rotation forest algorithm to predict the interactions among proteins 期刊论文
SOFT COMPUTING, 2018, 卷号: 22, 期号: 10, 页码: 3373-3381
Authors:  Wang, L (Wang, Lei);  You, ZH (You, Zhu-Hong);  Xia, SX (Xia, Shi-Xiong);  Chen, X (Chen, Xing);  Yan, X (Yan, Xin);  Zhou, Y (Zhou, Yong);  Liu, F (Liu, Feng)
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Rotation Forest  Ensemble Learning  Bioinformatics  Support Vector Machine  
A Systematic Prediction of Drug-Target Interactions Using Molecular Fingerprints and Protein Sequences 期刊论文
CURRENT PROTEIN & PEPTIDE SCIENCE, 2018, 卷号: 19, 期号: 5, 页码: 468-478
Authors:  Huang, YA (Huang, Yu-An);  You, ZH (You, Zhu-Hong);  Chen, X (Chen, Xing)
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Drug-target Interactions  Pseudo Substitution Matrix Representation  Drug Substructure Fingerprint  Extremely Randomized Trees  Computational Model  
PCLPred: A Bioinformatics Method for Predicting Protein-Protein Interactions by Combining Relevance Vector Machine Model with Low-Rank Matrix Approximation 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 卷号: 19, 期号: 4, 页码: 1-13
Authors:  Li, LP (Li, Li-Ping)[ 1 ];  Wang, YB (Wang, Yan-Bin)[ 2 ];  You, ZH (You, Zhu-Hong)[ 1 ];  Li, Y (Li, Yang)[ 1 ];  An, JY (An, Ji-Yong)[ 3 ]
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Protein-protein Interactions (Ppi)  Low Rank  Protein Sequence  Relevance Vector Machine (Rvm)  Evolutionary Information  
Using Two-dimensional Principal Component Analysis and Rotation Forest for Prediction of Protein-Protein Interactions 期刊论文
SCIENTIFIC REPORTS, 2018, 卷号: 8, 期号: 12874, 页码: 1-9
Authors:  Wang, L (Wang, Lei)[ 1,2 ];  You, ZH (You, Zhu-Hong)[ 2 ];  Yan, X (Yan, Xin)[ 4 ];  Xia, SX (Xia, Shi-Xiong)[ 3 ];  Liu, F (Liu, Feng)[ 5 ];  Li, LP (Li, Li-Ping)[ 2 ];  Zhang, W (Zhang, Wei)[ 1 ];  Zhou, Y (Zhou, Yong)[ 3 ]
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An Ensemble Classifier with Random Projection for Predicting Protein-Protein Interactions Using Sequence and Evolutionary Information 期刊论文
APPLIED SCIENCES-BASEL, 2018, 卷号: 8, 期号: 1, 页码: 1-15
Authors:  Song, XY (Song, Xiao-Yu);  Chen, ZH (Chen, Zhan-Heng);  Sun, XY (Sun, Xiang-Yang);  You, ZH (You, Zhu-Hong);  Li, LP (Li, Li-Ping);  Zhao, Y (Zhao, Yang)
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Protein-protein Interactions  Position-specific Scoring Matrix  Random Projection Ensemble Classifier  Support Vector Machine  
RFDT: A Rotation Forest-based Predictor for Predicting Drug-Target Interactions Using Drug Structure and Protein Sequence Information 期刊论文
CURRENT PROTEIN & PEPTIDE SCIENCE, 2018, 卷号: 19, 期号: 5, 页码: 445-454
Authors:  Wang, L (Wang, Lei);  You, ZH (You, Zhu-Hong);  Chen, X (Chen, Xing);  Yan, X (Yan, Xin);  Liu, G (Liu, Gang);  Zhang, W (Zhang, Wei)
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Target Interactions  Position-specific Scoring Matrix  Auto Covariance  Rotation Forest  Support Vector Machine  Drug Substructure Fingerprint  
Predicting protein-protein interactions from protein sequences by a stacked sparse autoencoder deep neural network 期刊论文
MOLECULAR BIOSYSTEMS, 2017, 卷号: 13, 期号: 7, 页码: 1336-1344
Authors:  Wang, YB (Wang, Yan-Bin);  You, ZH (You, Zhu-Hong);  Li, X (Li, Xiao);  Jiang, TH (Jiang, Tong-Hai);  Chen, X (Chen, Xing);  Zhou, X (Zhou, Xi);  Wang, L (Wang, Lei)
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An ensemble approach for large-scale identification of protein-protein interactions using the alignments of multiple sequences 期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 3, 页码: 5149-5159
Authors:  Wang, L (Wang, Lei);  You, ZH (You, Zhu-Hong);  Chen, X (Chen, Xing);  Li, JQ (Li, Jian-Qiang);  Yan, X (Yan, Xin);  Zhang, W (Zhang, Wei);  Huang, YA (Huang, Yu-An)
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Disease  Position-specific Scoring Matrix  Multiple Sequences Alignments  Cancer  
Prediction of protein-protein interactions by label propagation with protein evolutionary and chemical information derived from heterogeneous network 期刊论文
JOURNAL OF THEORETICAL BIOLOGY, 2017, 卷号: 430, 期号: 10, 页码: 9-20
Authors:  Wen, YT (Wen, Yu-Ting);  Lei, HJ (Lei, Hai-Jun);  You, ZH (You, Zhu-Hong);  Lei, BY (Lei, Bai-Ying);  Chen, X (Chen, Xing);  Li, LP (Li, Li-Ping)
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Protein-protein Interactions  Prediction  Similarity Network Fusion  Label Propagation Algorithm