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Chemical components of Hyssopus seravshanicus: antioxidant activity, activations of melanogenesis and tyrosinase, and quantitative determination by UPLC-DAD
Shomirzoeva, O (Shomirzoeva, Omina)[ 1,2,3 ]; Li, J (Li, Jun)[ 1,2 ]; Numonov, S (Numonov, Sodik)[ 1,2 ]; Mamat, N (Mamat, Nuramina)[ 1,2,3 ]; Shataer, D (Shataer, Dilireba)[ 1,2,3 ]; Lu, XY (Lu, Xueying)[ 1,2 ]; Aisa, HA (Aisa, Haji Abker)[ 1,2 ]
2019
Source PublicationNATURAL PRODUCT RESEARCH
ISSN1478-6419
Volume33Issue:6Pages:866-870
Abstract

Hyssopus seravshanicus (Dubj.) Pazij has been used as traditional herb and food due to its wide biological properties. Seventeen known compounds were isolated from the ethyl acetate fraction. Their structures were identified by spectroscopic data and comparison with published data. Among them, 14 ones were identified from H. seravshanicus for the first time. DPPH and ABTS radical scavenging activities for crude ethanol extract (CEE), ethyl acetate fraction (EAF), butanol fraction (BF) and compounds 1, 3, 8, 10, 11 and 13 were performed. CEE, compounds 1, 3, 11 and 13 exhibited potent antioxidant activities. Compound 1 was found to increase the melanin content and tyrosinase activity of B16 melanoma cells. Moreover, the quantitative estimation of compound 1 in the ethyl acetate fraction was carried out by UPLC-DAD and the method was validated. This is the first report on the isolation and bioactivity research on the non-valotile components of H. seravshanicus.

KeywordHyssopus seravshanicus phenolic compounds antioxidant melanogenesis tyrosinase quantitative determination
DOI10.1080/14786419.2017.1408105
Indexed BySCI
WOS IDWOS:000466606100016
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Document Type期刊论文
Identifierhttp://ir.xjipc.cas.cn/handle/365002/5789
Collection省部共建新疆特有药用资源利用重点实验室
Corresponding AuthorAisa, HA (Aisa, Haji Abker)[ 1,2 ]
Affiliation1.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Key Lab Plant Resources & Chem Arid Zone, Urumqi, Peoples R China
2.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, State Key Lab Basis Xinjiang Indigenous Med Plant, Urumqi, Peoples R China
3.Univ Chinese Acad Sci, Beijing, Peoples R China
Recommended Citation
GB/T 7714
Shomirzoeva, O ,Li, J ,Numonov, S ,et al. Chemical components of Hyssopus seravshanicus: antioxidant activity, activations of melanogenesis and tyrosinase, and quantitative determination by UPLC-DAD[J]. NATURAL PRODUCT RESEARCH,2019,33(6):866-870.
APA Shomirzoeva, O .,Li, J .,Numonov, S .,Mamat, N .,Shataer, D .,...&Aisa, HA .(2019).Chemical components of Hyssopus seravshanicus: antioxidant activity, activations of melanogenesis and tyrosinase, and quantitative determination by UPLC-DAD.NATURAL PRODUCT RESEARCH,33(6),866-870.
MLA Shomirzoeva, O ,et al."Chemical components of Hyssopus seravshanicus: antioxidant activity, activations of melanogenesis and tyrosinase, and quantitative determination by UPLC-DAD".NATURAL PRODUCT RESEARCH 33.6(2019):866-870.
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