XJIPC OpenIR  > 省部共建新疆特有药用资源利用重点实验室
Identification, synthesis, and control of efinaconazole impurities
Zhu, FQ (Zhu, Fuqiang)[ 1,2 ]; Zhang, J (Zhang, Jian)[ 3 ]; Xiamuxi, H (Xiamuxi, Hainimu)[ 1,2 ]; Chen, WM (Chen, Weiming)[ 1,2 ]; Hu, TW (Hu, Tianwen)[ 3 ]; Yang, XJ (Yang, Xiaojun)[ 3 ]; Tian, GH (Tian, Guanghui)[ 3 ]; Ni, RY (Ni, Runyan)[ 3 ]; Li, J (Li, Jian)[ 3 ]; Suo, J (Suo, Jin)[ 4 ]; Xie, YC (Xie, Yuanchao)[ 4 ]; Shen, JS (Shen, Jingshan)[ 4 ]; Aisa, HA (Aisa, Haji A.)[ 1 ]; He, Y (He, Yang)[ 4 ]
2018
Source PublicationPHARMAZIE
ISSN0031-7144
Volume73Issue:8Pages:438-441
Abstract

Impurities A-F were observed, identified, and confirmed during the efinaconazole production process. The possible formation pathways of the mentioned impurities were understood, and thereafter, a controlling strategy was established by locating the proper process parameters with the consideration of efficient cost and less waste as well. This impurity investigation is also essential for quality control of consistently delivering of qualified efinaconazole API.

DOI10.1691/ph.2018.8059
Indexed BySCI
WOS IDWOS:000442458400003
Citation statistics
Document Type期刊论文
Identifierhttp://ir.xjipc.cas.cn/handle/365002/5570
Collection省部共建新疆特有药用资源利用重点实验室
资源化学研究室
Corresponding AuthorAisa, HA (Aisa, Haji A.)[ 1 ]
Affiliation1.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Key Lab Plant Resources & Chem Arid Reg, South Beijing Rd 40-1, Urumqi 830011, Xinjiang, Peoples R China
2.Univ Chinese Acad Sci, Beijing, Peoples R China
3.Topharman Shanghai Co Ltd, Shanghai, Peoples R China
4.Chinese Acad Sci, Shanghai Inst Mat Med, CAS Key Lab Receptor Res, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R China
Recommended Citation
GB/T 7714
Zhu, FQ ,Zhang, J ,Xiamuxi, H ,et al. Identification, synthesis, and control of efinaconazole impurities[J]. PHARMAZIE,2018,73(8):438-441.
APA Zhu, FQ .,Zhang, J .,Xiamuxi, H .,Chen, WM .,Hu, TW .,...&He, Y .(2018).Identification, synthesis, and control of efinaconazole impurities.PHARMAZIE,73(8),438-441.
MLA Zhu, FQ ,et al."Identification, synthesis, and control of efinaconazole impurities".PHARMAZIE 73.8(2018):438-441.
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