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Diversity-oriented synthesis of amide derivatives of tricyclic thieno[2,3-d]pyrimidin-4(3H)-ones and evaluation of their influence on melanin synthesis in murine B16 cells
Nie, LF (Nie, Li Fei); Huang, GZ (Huang, Guozheng); Bozorov, K (Bozorov, Khurshed); Zhao, JY (Zhao, Jiangyu); Niu, C (Niu, Chao); Sagdullaev, SS (Sagdullaev, Shamansur S.); Aisa, HA (Aisa, Haji A.)
2018
Source PublicationHETEROCYCLIC COMMUNICATIONS
ISSN0793-0283
Volume24Issue:1Pages:43-50
Abstract

A diversity-oriented synthesis of amide-containing thieno[2,3-d]pyrimidin-4(3H)-ones is reported. All compounds were tested for their influence on melanin synthesis in murine B16 cells. The azepine fragment in thieno[2,3-d]pyrimidin-4(3H)-one skeleton significantly increases the melanin content.

KeywordMelanin Synthesis Murine B16 Cells Vitiligo Thieno[2 3-d]Pyrimidin-4(3h)-one
DOI10.1515/hc-2017-0256
Indexed BySCI
WOS IDWOS:000423989400008
Citation statistics
Document Type期刊论文
Identifierhttp://ir.xjipc.cas.cn/handle/365002/5498
Collection省部共建新疆特有药用资源利用重点实验室
资源化学研究室
Corresponding AuthorAisa, HA (Aisa, Haji A.)
Affiliation1.Chinese Acad Sci, Key Lab Plant Resources & Chem Arid Reg, State Key Lab Basis Xinjiang Indigenous Med Plant, Xinjiang Tech Inst Phys & Chem, South Beijing Rd 40-1, Urumqi 830011, Peoples R China
2.Acad Sci Uzbek, Inst Chem Plant Subst, MirzoUlugbek Str 77, Tashkent 100170, Uzbekistan
Recommended Citation
GB/T 7714
Nie, LF ,Huang, GZ ,Bozorov, K ,et al. Diversity-oriented synthesis of amide derivatives of tricyclic thieno[2,3-d]pyrimidin-4(3H)-ones and evaluation of their influence on melanin synthesis in murine B16 cells[J]. HETEROCYCLIC COMMUNICATIONS,2018,24(1):43-50.
APA Nie, LF .,Huang, GZ .,Bozorov, K .,Zhao, JY .,Niu, C .,...&Aisa, HA .(2018).Diversity-oriented synthesis of amide derivatives of tricyclic thieno[2,3-d]pyrimidin-4(3H)-ones and evaluation of their influence on melanin synthesis in murine B16 cells.HETEROCYCLIC COMMUNICATIONS,24(1),43-50.
MLA Nie, LF ,et al."Diversity-oriented synthesis of amide derivatives of tricyclic thieno[2,3-d]pyrimidin-4(3H)-ones and evaluation of their influence on melanin synthesis in murine B16 cells".HETEROCYCLIC COMMUNICATIONS 24.1(2018):43-50.
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