XJIPC OpenIR  > 省部共建新疆特有药用资源利用重点实验室
Traditional Chinese medicinal herbs as potential AChE inhibitors for anti-Alzheimer's disease: A review
Jiang, YY (Jiang, Yingying); Gao, HW (Gao, Hongwei); Turdu, G (Turdu, Gulmira); Gao, HW
2017
Source PublicationBIOORGANIC CHEMISTRY
ISSN0045-2068
Volume75Issue:12Pages:50-61
Abstract

Alzheimer's disease (AD) is a progressive neurodegenerative disease affecting 25 million people worldwide, and cholinergic hypothesis is considered as an important hypotheses in the processes of improving cognitive function and recognition skills in recent years. For the long-term treatment of AD, traditional Chinese medicine are particularly suitable for drug discovery. In this review, we sum up six traditional Chinese medicinal herbs concerned with development of AChEIs, including Herba Epimedii, Coptis Chinensis Franch, Rhizoma Curcumae Longae, Green tea, Ganoderma, Panax Ginseng. The listed compounds based on these herbs are belonging to six classes Flavonoids, Alkaloids, Ketones, Polyphenols, Terpenoid and Saponins, respectively. These compounds could be very promising agents in the search for potent anti-Alzheimer's drugs.

KeywordAlzheimer's Disease Tcm Acetylcholinesterase Inhibitors
DOI10.1016/j.bioorg.2017.09.004
Indexed BySCI
WOS IDWOS:000417682200005
Citation statistics
Document Type期刊论文
Identifierhttp://ir.xjipc.cas.cn/handle/365002/5484
Collection省部共建新疆特有药用资源利用重点实验室
Corresponding AuthorGao, HW
AffiliationChinese Acad Sci, Key Lab Plant Resources & Chem Arid Reg, Xinjiang Tech Inst Phys & Chem, Urumqi 830011, Peoples R China
Recommended Citation
GB/T 7714
Jiang, YY ,Gao, HW ,Turdu, G ,et al. Traditional Chinese medicinal herbs as potential AChE inhibitors for anti-Alzheimer's disease: A review[J]. BIOORGANIC CHEMISTRY,2017,75(12):50-61.
APA Jiang, YY ,Gao, HW ,Turdu, G ,&Gao, HW.(2017).Traditional Chinese medicinal herbs as potential AChE inhibitors for anti-Alzheimer's disease: A review.BIOORGANIC CHEMISTRY,75(12),50-61.
MLA Jiang, YY ,et al."Traditional Chinese medicinal herbs as potential AChE inhibitors for anti-Alzheimer's disease: A review".BIOORGANIC CHEMISTRY 75.12(2017):50-61.
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