XJIPC OpenIR  > 省部共建新疆特有药用资源利用重点实验室
New coumarin from the roots of Prangos pabularia.
Numonov, Sodik; Bobakulov, Khayrulla; Numonova, Mukhabbat; Sharopov, Farukh; Setzer, William N; Khalilov, Qosimjon; Begmatov, Nurmirza; Habasi,
2017
Source PublicationNatural product research
Issue12Pages:1-8
Abstract

The new coumarin 1, yuganin A (7-methoxy-8-((1S,2S)-1,2,3-trihydroxy-3-methylbutyl)-2H-chromen-2-one) along with nine known coumarins, heraclenol 3'-O-beta-D-glucopyranoside (2), oxypeucedanin hydrate 3'-O-beta-D-glucopyranoside (3), heraclenol (4), oxypeucedanin hydrate (5), osthole (6), oxypeucedanin (7), heraclenin (8), isoimperatorin (9), imperatorin (10) and the disaccharide sucrose (11), have been isolated from the roots of Prangos pabularia, and the structures of these isolated compounds were elucidated by spectroscopic means, especially, UV, HR-ESIMS, and 1D and 2D NMR spectroscopy. Furthermore, the anti-melanogenic effect of yuganin A and its inhibitory effect on B16 cells were evaluated. Yuganin A may be useful in the treatment of hyperpigmentation and as a skin-whitening agent in the cosmetics industry.

KeywordB16 Melanoma Cells Nmr Prangos Pabularia Coumarins Furanocoumarins Yuganin a
DOI10.1080/14786419.2017.1413558
Indexed BySCI
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Document Type期刊论文
Identifierhttp://ir.xjipc.cas.cn/handle/365002/5252
Collection省部共建新疆特有药用资源利用重点实验室
AffiliationKey Laboratory of Plant Resources and Chemistry in Arid Regions, Xinjiang Technical Institute of Physics and Chemistry , Chinese Academy of Sciences , Urumqi , P. R. China.
Recommended Citation
GB/T 7714
Numonov, Sodik,Bobakulov, Khayrulla,Numonova, Mukhabbat,et al. New coumarin from the roots of Prangos pabularia.[J]. Natural product research,2017(12):1-8.
APA Numonov, Sodik.,Bobakulov, Khayrulla.,Numonova, Mukhabbat.,Sharopov, Farukh.,Setzer, William N.,...&Habasi,.(2017).New coumarin from the roots of Prangos pabularia..Natural product research(12),1-8.
MLA Numonov, Sodik,et al."New coumarin from the roots of Prangos pabularia.".Natural product research .12(2017):1-8.
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