New coumarin from the roots of Prangos pabularia.
Numonov, Sodik; Bobakulov, Khayrulla; Numonova, Mukhabbat; Sharopov, Farukh; Setzer, William N; Khalilov, Qosimjon; Begmatov, Nurmirza; Habasi,
2017
发表期刊Natural product research
期号12页码:1-8
摘要

The new coumarin 1, yuganin A (7-methoxy-8-((1S,2S)-1,2,3-trihydroxy-3-methylbutyl)-2H-chromen-2-one) along with nine known coumarins, heraclenol 3'-O-beta-D-glucopyranoside (2), oxypeucedanin hydrate 3'-O-beta-D-glucopyranoside (3), heraclenol (4), oxypeucedanin hydrate (5), osthole (6), oxypeucedanin (7), heraclenin (8), isoimperatorin (9), imperatorin (10) and the disaccharide sucrose (11), have been isolated from the roots of Prangos pabularia, and the structures of these isolated compounds were elucidated by spectroscopic means, especially, UV, HR-ESIMS, and 1D and 2D NMR spectroscopy. Furthermore, the anti-melanogenic effect of yuganin A and its inhibitory effect on B16 cells were evaluated. Yuganin A may be useful in the treatment of hyperpigmentation and as a skin-whitening agent in the cosmetics industry.

关键词B16 Melanoma Cells Nmr Prangos Pabularia Coumarins Furanocoumarins Yuganin a
DOI10.1080/14786419.2017.1413558
收录类别SCI
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文献类型期刊论文
条目标识符http://ir.xjipc.cas.cn/handle/365002/5252
专题省部共建新疆特有药用资源利用重点实验室
作者单位Key Laboratory of Plant Resources and Chemistry in Arid Regions, Xinjiang Technical Institute of Physics and Chemistry , Chinese Academy of Sciences , Urumqi , P. R. China.
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GB/T 7714
Numonov, Sodik,Bobakulov, Khayrulla,Numonova, Mukhabbat,et al. New coumarin from the roots of Prangos pabularia.[J]. Natural product research,2017(12):1-8.
APA Numonov, Sodik.,Bobakulov, Khayrulla.,Numonova, Mukhabbat.,Sharopov, Farukh.,Setzer, William N.,...&Habasi,.(2017).New coumarin from the roots of Prangos pabularia..Natural product research(12),1-8.
MLA Numonov, Sodik,et al."New coumarin from the roots of Prangos pabularia.".Natural product research .12(2017):1-8.
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