Recent developments regarding the use of thieno[2,3-d]pyrimidin-4-one derivatives in medicinal chemistry, with a focus on their synthesis and anticancer properties
Bozorov, K (Bozorov, Khurshed); Zhao, JY (Zhao, Jiang-Yu); Elmuradov, B (Elmuradov, Burkhon); Pataer, A (Pataer, Apar); Aisa, HA (Aisa, Haji A.); Aisa, HA
2015
发表期刊EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
卷号102期号:9页码:552-573
摘要

It is generally understood that the antitumor properties of synthetic heterocyclic compounds are among the most powerful properties that can be made use in medicinal chemistry. More specifically, their substantial cytotoxic effects against different types of human tumor cells, in addition to their roles as enzymes or receptors for various kinase inhibitors, make them critically important. In recent years, thieno[2,3-d]pyrimidin-4-one derivatives (TPs), which are analogs of quinazoline alkaloids, have frequently attracted the interest of medicinal chemistry researchers due to their promising anticancer properties. The present study is a review of the latest advances (i.e., since 2006) in TP derivative-related research, with a focus on how such derivatives are synthesized and on their anticancer activities.

关键词Synthesis Thieno[2 Anticancer 3-d]Pyrimidin-4-one Derivatives Cytotoxic Effect Kinase Inhibitors
DOI10.1016/j.ejmech.2015.08.018
收录类别SCI
WOS记录号WOS:000361922600046
引用统计
被引频次:18[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.xjipc.cas.cn/handle/365002/5139
专题省部共建新疆特有药用资源利用重点实验室
通讯作者Aisa, HA
作者单位1.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Key Lab Plant Resources & Chem Arid Reg, Urumqi 830011, Xinjiang, Peoples R China
2.Acad Sci Uzbek, Inst,Chem Plant Subst, Tashkent 100170, Uzbekistan
3.Univ Texas MD Anderson Canc Ctr, Dept Thorac & Cardiovasc Surg, Houston, TX 77030 USA
推荐引用方式
GB/T 7714
Bozorov, K ,Zhao, JY ,Elmuradov, B ,et al. Recent developments regarding the use of thieno[2,3-d]pyrimidin-4-one derivatives in medicinal chemistry, with a focus on their synthesis and anticancer properties[J]. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,2015,102(9):552-573.
APA Bozorov, K ,Zhao, JY ,Elmuradov, B ,Pataer, A ,Aisa, HA ,&Aisa, HA.(2015).Recent developments regarding the use of thieno[2,3-d]pyrimidin-4-one derivatives in medicinal chemistry, with a focus on their synthesis and anticancer properties.EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,102(9),552-573.
MLA Bozorov, K ,et al."Recent developments regarding the use of thieno[2,3-d]pyrimidin-4-one derivatives in medicinal chemistry, with a focus on their synthesis and anticancer properties".EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 102.9(2015):552-573.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
Recent developments (1515KB)期刊论文作者接受稿开放获取CC BY-NC-SA浏览 请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Bozorov, K (Bozorov, Khurshed)]的文章
[Zhao, JY (Zhao, Jiang-Yu)]的文章
[Elmuradov, B (Elmuradov, Burkhon)]的文章
百度学术
百度学术中相似的文章
[Bozorov, K (Bozorov, Khurshed)]的文章
[Zhao, JY (Zhao, Jiang-Yu)]的文章
[Elmuradov, B (Elmuradov, Burkhon)]的文章
必应学术
必应学术中相似的文章
[Bozorov, K (Bozorov, Khurshed)]的文章
[Zhao, JY (Zhao, Jiang-Yu)]的文章
[Elmuradov, B (Elmuradov, Burkhon)]的文章
相关权益政策
暂无数据
收藏/分享
文件名: Recent developments regarding the use of thieno[2,3-d]pyrimidin-4-one derivatives in medicinal chemistry, with a focus on their synthesis and anticancer properties.pdf
格式: Adobe PDF
此文件暂不支持浏览
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。