XJIPC OpenIR  > 省部共建新疆特有药用资源利用重点实验室
Two new triterpenes from Euphorbia alatavica
Rozimama, R (Rozimama, Rushangul); Kehrimen, N (Kehrimen, Nurmuhammat); Gao, J (Gao, Jie); Ma, HR (Ma, Hai-Rong); Aisa, HA (Aisa, Haji Akber)
2017
Source PublicationJOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
ISSN1028-6020
Volume19Issue:10Pages:966-973
Abstract

A phytochemical investigation on Euphorbia alatavica Boiss resulted in the isolation of nine compounds, including two new ones, alatavolide and alatavoic acid (1-2). Chemical structures of these compounds were established on the basis of 1D, 2D NMR, and HR-MS techniques, and by comparison with data reported in the literature. Compounds 1, 2, 4, 6, 8, and 9 were screened for cytotoxicity using the MTT assay. Among these compounds, the new compound 2 showed moderate cytotoxicity against Hela, MCF-7 and A549 cell lines (IC50 values of 16.4 +/- 3.2, 14.5 +/- 2.8, 22.3 +/- 3.1 mu M, respectively), while the known compound 8 exhibited the most potent cytotoxicity with the IC50 values of 6.5 +/- 3.1, 1.9 +/- 0.9, 8.6 +/- 3.5 mu M, respectively.

KeywordEuphorbia Alatavica Triterpene Bioactivity
DOI10.1080/10286020.2017.1307835
Indexed BySCI
WOS IDWOS:000413701800004
Citation statistics
Cited Times:1[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.xjipc.cas.cn/handle/365002/5087
Collection省部共建新疆特有药用资源利用重点实验室
资源化学研究室
Corresponding AuthorAisa, HA (Aisa, Haji Akber)
Affiliation1.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Key Lab Plant Resources & Chem Arid Zone, Urumqi 830011, Peoples R China
2.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, State Key Lab Basis Xinjiang Indigenous Med Plant, Urumqi 830011, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100039, Peoples R China
Recommended Citation
GB/T 7714
Rozimama, R ,Kehrimen, N ,Gao, J ,et al. Two new triterpenes from Euphorbia alatavica[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2017,19(10):966-973.
APA Rozimama, R ,Kehrimen, N ,Gao, J ,Ma, HR ,&Aisa, HA .(2017).Two new triterpenes from Euphorbia alatavica.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,19(10),966-973.
MLA Rozimama, R ,et al."Two new triterpenes from Euphorbia alatavica".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 19.10(2017):966-973.
Files in This Item:
File Name/Size DocType Version Access License
Two new triterpenes (1005KB)期刊论文作者接受稿开放获取CC BY-NC-SAView Application Full Text
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Rozimama, R (Rozimama, Rushangul)]'s Articles
[Kehrimen, N (Kehrimen, Nurmuhammat)]'s Articles
[Gao, J (Gao, Jie)]'s Articles
Baidu academic
Similar articles in Baidu academic
[Rozimama, R (Rozimama, Rushangul)]'s Articles
[Kehrimen, N (Kehrimen, Nurmuhammat)]'s Articles
[Gao, J (Gao, Jie)]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Rozimama, R (Rozimama, Rushangul)]'s Articles
[Kehrimen, N (Kehrimen, Nurmuhammat)]'s Articles
[Gao, J (Gao, Jie)]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: Two new triterpenes from Euphorbia alatavica.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.