Upregulation of Melanogenesis and Tyrosinase Activity: Potential Agents for Vitiligo
Niu, C (Niu, Chao); Aisa, HA (Aisa, Haji A.); Aisa, HA
2017
发表期刊MOLECULES
卷号22期号:8
摘要

Melanin, the compound primarily responsible in humans for hair, eye and skin pigmentation, is produced by melanocytes through a complicated process called melanogenesis that is catalyzed by tyrosinase and other tyrosinase-related proteins. The abnormal loss of melanin causes dermatological problems such as vitiligo. Hence the regulation of melanogenesis and tyrosinase activity is very important for treating hypopigmentary disorders. Many melanogenesis stimulators have been discovered during the past decade. This article reviews recent advances in research on extracts and active ingredients of plants, synthesized compounds with stimulating effect on melanin synthesis and tyrosinase activity, as well as their influence on the expression of related proteins and possible signaling pathways for the design and development of novel anti-vitiligo agents.

关键词Melanogenesis Tyrosinase Activity Vitiligo Plant Extracts Natural Products Synthesized Derivatives Analogues
DOI10.3390/molecules22081303
收录类别SCI
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文献类型期刊论文
条目标识符http://ir.xjipc.cas.cn/handle/365002/5047
专题省部共建新疆特有药用资源利用重点实验室
通讯作者Aisa, HA
作者单位1.Chinese Acad Sci, Key Lab Plant Resources & Chem Arid Zone, Urumqi 830011, Peoples R China
2.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, State Key Lab Basis Xinjiang Indigenous Med Plant, Urumqi 830011, Peoples R China
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GB/T 7714
Niu, C ,Aisa, HA ,Aisa, HA. Upregulation of Melanogenesis and Tyrosinase Activity: Potential Agents for Vitiligo[J]. MOLECULES,2017,22(8).
APA Niu, C ,Aisa, HA ,&Aisa, HA.(2017).Upregulation of Melanogenesis and Tyrosinase Activity: Potential Agents for Vitiligo.MOLECULES,22(8).
MLA Niu, C ,et al."Upregulation of Melanogenesis and Tyrosinase Activity: Potential Agents for Vitiligo".MOLECULES 22.8(2017).
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