Three new elemanolides from the seeds of Vernonia anthelmintica.
Turak, Ablajan; Aisa, Haji Akber
2017
发表期刊Journal of Asian natural products research
期号7页码:1-8
摘要Three new elemanolides, named vernonilides D (1), E (2), and F (3), along with four known sesquiterpenoids, including two elemanolides (4, 5), a guaianolide (6), and a germacranolide (7) were isolated from the seeds of Vernonia anthelmintica. The structures of them were elucidated based on 1D and 2D NMR experiments and comparison with published data. Cytotoxicity of the compounds against four human tumor cell lines was assayed. 6 showed strongly inhibitory effect against HCT-15 and PC-3 cell lines with IC50 values of 0.56 and 0.69muM, respectively. The new compounds showed moderate cytotoxicity against four cell lines with IC50 values ranging from 9.1 to 28.1muM.
关键词Compositae Vernonia Anthelmintica Cytotoxicity Elemanolide Sesquiterpenoid
DOI10.1080/10286020.2017.1343304
收录类别SCI
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文献类型期刊论文
条目标识符http://ir.xjipc.cas.cn/handle/365002/4842
专题省部共建新疆特有药用资源利用重点实验室
作者单位a State Key Laboratory Basis of Xinjiang Indigenous Medicinal Plants Resource Utilization , Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences , Urumqi 830011 , China.
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Turak, Ablajan,Aisa, Haji Akber. Three new elemanolides from the seeds of Vernonia anthelmintica.[J]. Journal of Asian natural products research,2017(7):1-8.
APA Turak, Ablajan,&Aisa, Haji Akber.(2017).Three new elemanolides from the seeds of Vernonia anthelmintica..Journal of Asian natural products research(7),1-8.
MLA Turak, Ablajan,et al."Three new elemanolides from the seeds of Vernonia anthelmintica.".Journal of Asian natural products research .7(2017):1-8.
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