XJIPC OpenIR  > 省部共建新疆特有药用资源利用重点实验室
维药阿里红中2个新三萜酸成分
韩建欣;袁涛
2017
Source Publication中国中药杂志
ISSN1001-5302
Volume42Issue:7Pages:1225-1228
Abstract

该研究旨在阐明维药阿里红的药效物质基础。采用各种现代色谱手段(MCI,ODS,硅胶等柱色谱以及半制备高效液相色谱)从阿里红甲醇提取物中分离得到2个新的羊毛甾烷型三萜酸成分,通过一维,二维核磁共振、高分辨质谱等波谱手段鉴定其结构为12β,15α-dihydroxy-24-methyl-3,23-dioxo-lanosta-7,9(11)-dien-26-oic acid(1),3α,12β-dihydroxy-24-methyl-7,23-dioxo-lanosta-8-en-26-oic acid(2)。体外抗炎和细胞毒活性测试显示,化合物1和2均未表现出抑制LPS诱导RAW264.7细胞NO的产生,以及抑制肝癌细胞HepG2生长的活性。

Keyword维药 阿里红 三萜酸 抗炎 细胞毒
Indexed ByCSCD
CSCD IDCSCD:5977209
Citation statistics
Cited Times:1[CSCD]   [CSCD Record]
Document Type期刊论文
Identifierhttp://ir.xjipc.cas.cn/handle/365002/4810
Collection省部共建新疆特有药用资源利用重点实验室
Affiliation中国科学院干旱区植物资源化学重点实验室;新疆特有药用资源利用重点实验室;中国科学院新疆理化技术研究所;中国科学院大学
Recommended Citation
GB/T 7714
韩建欣;袁涛. 维药阿里红中2个新三萜酸成分[J]. 中国中药杂志,2017,42(7):1225-1228.
APA 韩建欣;袁涛.(2017).维药阿里红中2个新三萜酸成分.中国中药杂志,42(7),1225-1228.
MLA 韩建欣;袁涛."维药阿里红中2个新三萜酸成分".中国中药杂志 42.7(2017):1225-1228.
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