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Controllable synthesis of SiO2 nanoparticles: effects of ammonia and tetraethyl orthosilicate concentration
Yan, Y (Yan, Yue); Fu, J (Fu, Jie); Xu, L (Xu, Ling); Wang, TF (Wang, Tianfu); Lu, XY (Lu, Xiuyang)
2016
Source PublicationMICRO & NANO LETTERS
ISSN1750-0443
Volume11Issue:12Pages:885-889
Abstract

SiO2 nanoparticles can be used as drug carriers in drug delivery systems, wherein the size of the nanoparticles plays a vital role in their distribution in vivo. SiO2 nanoparticles were synthesised using the Stober method and characterised by dynamic light scattering and scanning electron microscopy. The effects of the ammonia concentration, tetraethyl orthosilicate (TEOS) concentration, water loading and alcohol type on the size and dispersion of the SiO2 nanoparticles were investigated. The results showed that the concentration of ammonia was the most important factor in dictating the size of the SiO2 nanoparticles. The size of the particles increased with increasing ammonia and TEOS concentrations. Increasing the water loading caused a reduction in the particle size but an increase in the dispersion. Both the particle size and dispersion increased with increasing alcohol carbon number. Linear relationships were observed between the SiO2 particle size and the concentrations of ammonia and TEOS, which could be used to control the size of SiO2 nanoparticles during synthesis.

KeywordSilicon Compounds Nanoparticles Nanofabrication Ammonia Organic Compounds Particle Size Controllable Synthesis Ammonia-tetraethyl Orthosilicate Concentration Effects Drug Carriers Drug Delivery Systems Stober Method Dynamic Light Scattering Scanning Electron Microscopy Nanoparticle Size Dispersion Sio2 Nh3
DOI10.1049/mnl.2016.0434
WOS IDWOS:000389323100025
Citation statistics
Cited Times:1[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.xjipc.cas.cn/handle/365002/4718
Collection环境科学与技术研究室
资源化学研究室
Affiliation1.Zhejiang Univ, Coll Chem & Biol Engn, Key Lab Biomass Chem Engn, Minist Educ, Hangzhou 310027, Zhejiang, Peoples R China
2.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Urumqi 830011, Peoples R China
Recommended Citation
GB/T 7714
Yan, Y ,Fu, J ,Xu, L ,et al. Controllable synthesis of SiO2 nanoparticles: effects of ammonia and tetraethyl orthosilicate concentration[J]. MICRO & NANO LETTERS,2016,11(12):885-889.
APA Yan, Y ,Fu, J ,Xu, L ,Wang, TF ,&Lu, XY .(2016).Controllable synthesis of SiO2 nanoparticles: effects of ammonia and tetraethyl orthosilicate concentration.MICRO & NANO LETTERS,11(12),885-889.
MLA Yan, Y ,et al."Controllable synthesis of SiO2 nanoparticles: effects of ammonia and tetraethyl orthosilicate concentration".MICRO & NANO LETTERS 11.12(2016):885-889.
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