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Two new sesquiterpenoid glycosides from the leaves of Lycium barbarum
Wang, Y (Wang, Yan); Zhao, B (Zhao, Bo); Ma, HR (Ma, Hai-Rong); Aisa, HA (Aisa, Haji Akber)
2016
Source PublicationJOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
ISSN1028-6020
Volume18Issue:9Pages:871-877
Abstract

Two new sesquiterpenoid glycosides, lyciumionosides A-B (1-2), together with four known compounds (3-6), were isolated from the leaves of Lycium barbarum. Their structures were mainly established on the basis of MS, 1D and 2D NMR spectroscopic techniques. The antiproliferative activities of compounds 1-5 were evaluated. Compound 1 showed highest inhibitory activity against A549 cells with IC50 value of 32.6 +/- 2.6 mu M, compound 3 showed highest inhibitory activity against PC-3 cells with IC50 value of 36.0 +/- 2.9 mu M, and compound 5 exhibited highest inhibitory activity against HeLa cells with IC50 value of 32.3 +/- 4.2 mu M.

KeywordSolanaceae Lycium Barbarum Sesquiterpenoid Glycosides Antiproliferative Activities
DOI10.1080/10286020.2016.1171756
Indexed BySCI
WOS IDWOS:000379739700008
Citation statistics
Cited Times:2[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.xjipc.cas.cn/handle/365002/4697
Collection省部共建新疆特有药用资源利用重点实验室
资源化学研究室
Corresponding AuthorAisa, HA (Aisa, Haji Akber)
Affiliation1.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Key Lab Plant Resources & Chem Arid Reg, Urumqi 830011, Peoples R China
2.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Key Lab Xinjiang Indigenous Med Plants Resource U, Urumqi 830011, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100039, Peoples R China
Recommended Citation
GB/T 7714
Wang, Y ,Zhao, B ,Ma, HR ,et al. Two new sesquiterpenoid glycosides from the leaves of Lycium barbarum[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2016,18(9):871-877.
APA Wang, Y ,Zhao, B ,Ma, HR ,&Aisa, HA .(2016).Two new sesquiterpenoid glycosides from the leaves of Lycium barbarum.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,18(9),871-877.
MLA Wang, Y ,et al."Two new sesquiterpenoid glycosides from the leaves of Lycium barbarum".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 18.9(2016):871-877.
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