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题名: A concise and enantioselective approach to the total synthesis of (-)-lasubine I
作者: Liu, Shengyang; Fan, Yuping; Peng, Xinxiang; Wang, Wei; Hua, Weiyi; Akber, Haji; Liao, Lixin
关键词: lasubine ; ring-closing metathesis ; Roush allylboration ; quinolizidine
刊名: TETRAHEDRON LETTERS
发表日期: 2006
DOI: 10.1016/j.tetlet.2006.08.137
卷: 47, 期:44, 页:7681-7684
收录类别: SCI
摘要: An efficient, enantioselective total synthesis of (-)-lasubine I (1) has been achieved in an overall 8.8% yield from readily available starting materials. The important features of this approach include the creation of stereogenic centers through two sequential highly stereoselective Roush allylborations and the use of S(N)2 cyclization and ring-closing metathesis reactions for the construction of the quinolizidine skeleton.
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内容类型: 期刊论文
URI标识: http://ir.xjipc.cas.cn/handle/365002/4130
Appears in Collections:资源化学研究室_期刊论文

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作者单位: Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Urumqi 830011, Peoples R China;China Pharmaceut Univ, Dept Med Chem, Nanjing 210009, Peoples R China;E China Univ Sci & Technol, Sch Pharm, Dept Med Chem, Shanghai 200237, Peoples R China;Univ New Mexico, Dept Chem, Albuquerque, NM 87131 USA;Chinese Acad Sci, Grad Sch, Shanghai Inst Mat Med, Shanghai Inst Biol Sci, Shanghai 201203, Peoples R China

Recommended Citation:
Liu, Shengyang,Fan, Yuping,Peng, Xinxiang,et al. A concise and enantioselective approach to the total synthesis of (-)-lasubine I[J]. TETRAHEDRON LETTERS,2006,47(44):7681-7684.
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