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题名:
SYNTHESIS OF RUPESTONIC ACID AMIDE DERIVATIVES AND THEIR in vitro ACTIVITY AGAINST TYPE A(3) AND B FLU VIRUS AND HERPES SIMPLEX I AND II
作者: Yong, J. -P.; Ajiaikebaier AiSa
关键词: synthesis ; rupestonic acid ; amide derivatives ; flu virus ; herpes simplex virus ; activity
刊名: CHEMISTRY OF NATURAL COMPOUNDS
发表日期: 2008
DOI: 10.1007/s10600-008-9050-y
卷: 44, 期:3, 页:311-314
收录类别: SCI
英文摘要: Derivatives of rupestonic acid (5a-e) were synthesized and evaluated preliminarily at the National Center for Drug Screening (PRC) for antiviral activity against type A(3) and B flu virus and HSV-I and HSV-II in order to improve the biological activity of rupestonic acid. It was found that compound 5b was more active than rupestonic acid against type A(3) flu virus.
WOS记录号: WOS:000260249700009
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内容类型: 期刊论文