XJIPC OpenIR  > 省部共建新疆特有药用资源利用重点实验室
Simultaneous quantification of seven flavonoids in Flos gossypii by LC
Wu, Tao; Abdulla, Rahima; Zhao, Yongxin; Yang, Yi; Chen, Jun; Aisa, Haji Akber
2008
Source PublicationCHROMATOGRAPHIA
ISSN0009-5893
Volume68Issue:5-6Pages:467-470
Abstract

A simple, reproducible and accurate RP-LC method has been developed for simultaneous analysis of seven flavonoids (quercimeritrin, hyperoside, isoquercetrin, astragalin, quercetin, quercetin-3'-glucoside, and tiliroside) in Flos Gossypii (FG), a drug used in Xinjiang, China. The analytes were separated on a C(18) column by elution with a gradient prepared from methanol, acetonitrile, and 0.2% aqueous phosphoric acid. The method was validated for linearity, accuracy, precision, sensitivity, and system suitability. It has been successfully used for evaluation of ten samples of different origin from Xinjiang, China. A similar pattern was observed for all the FG samples analyzed; quercimeritrin, isoquercetrin, and quercetin-3'-glucoside were the major compounds. The method is a simple, rapid, and reliable tool for quality control and may help reveal the correlation between the bioactivity of the FG and individual flavonoid content.

KeywordColumn Liquid Chromatography Flos Gossypii Method Validation Flavonoids Quantitative Analysis
DOI10.1365/s10337-008-0723-2
Indexed BySCI
WOS IDWOS:000259186700026
Citation statistics
Cited Times:3[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.xjipc.cas.cn/handle/365002/4089
Collection省部共建新疆特有药用资源利用重点实验室
Corresponding AuthorAisa, Haji Akber
AffiliationChinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Xinjiang Key Lab Plant Resources & Nat Prod Chem, Urumqi 830011, Peoples R China;Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
Recommended Citation
GB/T 7714
Wu, Tao,Abdulla, Rahima,Zhao, Yongxin,et al. Simultaneous quantification of seven flavonoids in Flos gossypii by LC[J]. CHROMATOGRAPHIA,2008,68(5-6):467-470.
APA Wu, Tao,Abdulla, Rahima,Zhao, Yongxin,Yang, Yi,Chen, Jun,&Aisa, Haji Akber.(2008).Simultaneous quantification of seven flavonoids in Flos gossypii by LC.CHROMATOGRAPHIA,68(5-6),467-470.
MLA Wu, Tao,et al."Simultaneous quantification of seven flavonoids in Flos gossypii by LC".CHROMATOGRAPHIA 68.5-6(2008):467-470.
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