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题名: Simultaneous quantification of seven flavonoids in Flos gossypii by LC
作者: Wu, Tao; Abdulla, Rahima; Zhao, Yongxin; Yang, Yi; Chen, Jun; Aisa, Haji Akber
通讯作者: Aisa, HA
关键词: column liquid chromatography ; Flos Gossypii ; method validation ; flavonoids ; quantitative analysis
刊名: CHROMATOGRAPHIA
发表日期: 2008
DOI: 10.1365/s10337-008-0723-2
卷: 68, 期:5-6, 页:467-470
收录类别: SCI
摘要: A simple, reproducible and accurate RP-LC method has been developed for simultaneous analysis of seven flavonoids (quercimeritrin, hyperoside, isoquercetrin, astragalin, quercetin, quercetin-3'-glucoside, and tiliroside) in Flos Gossypii (FG), a drug used in Xinjiang, China. The analytes were separated on a C(18) column by elution with a gradient prepared from methanol, acetonitrile, and 0.2% aqueous phosphoric acid. The method was validated for linearity, accuracy, precision, sensitivity, and system suitability. It has been successfully used for evaluation of ten samples of different origin from Xinjiang, China. A similar pattern was observed for all the FG samples analyzed; quercimeritrin, isoquercetrin, and quercetin-3'-glucoside were the major compounds. The method is a simple, rapid, and reliable tool for quality control and may help reveal the correlation between the bioactivity of the FG and individual flavonoid content.
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内容类型: 期刊论文
URI标识: http://ir.xjipc.cas.cn/handle/365002/4089
Appears in Collections:新疆维吾尔自治区植物资源化学重点实验室 _期刊论文

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作者单位: Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Xinjiang Key Lab Plant Resources & Nat Prod Chem, Urumqi 830011, Peoples R China;Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China

Recommended Citation:
Wu, Tao,Abdulla, Rahima,Zhao, Yongxin,et al. Simultaneous quantification of seven flavonoids in Flos gossypii by LC[J]. CHROMATOGRAPHIA,2008,68(5-6):467-470.
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