XJIPC OpenIR  > 省部共建新疆特有药用资源利用重点实验室
Synthesis, characterization, and antitumor activities of new palladium(II) complexes with 1-(alkyldithiocarbonyl)imidazoles
Hou, Xueling; Li, Xiaobo; Hemit, Helimay; Aisa, Haji Akber; Hou, XL
2014
Source PublicationJOURNAL OF COORDINATION CHEMISTRY
ISSN0095-8972
Volume67Issue:3Pages:461-469
Abstract

Pd(II) complexes with imidazole linked to dithiocarbamate derivatives were synthesized by reacting 1-(alkyldithiocarbonyl)-imidazoles with PdCl2 in a 2:1molar ratio. The complexes were characterized by elemental analyses, FT-IR, and H-1 NMR. The single crystal structure of 4 shows that the ligand is chelated by nitrogens in imidazole, instead of sulfur, to palladium. All synthesized compounds were tested for in vitro anticancer activities. Compound 5 had better activities in the HL-60 cell line and twofold better activities in the HeLa cell line than that of cisplatin.

KeywordDithiocarbamate Palladium Imidazole Antitumor Activity
DOI10.1080/00958972.2014.890717
Indexed BySCI
WOS IDWOS:000334074800004
Citation statistics
Document Type期刊论文
Identifierhttp://ir.xjipc.cas.cn/handle/365002/3804
Collection省部共建新疆特有药用资源利用重点实验室
资源化学研究室
Corresponding AuthorHou, XL
AffiliationChinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Key Lab Plant Resources & Chem Arid Zone, State Key Lab Basis Xinjiang Indigenous Med Plant, Urumqi, Peoples R China
Recommended Citation
GB/T 7714
Hou, Xueling,Li, Xiaobo,Hemit, Helimay,et al. Synthesis, characterization, and antitumor activities of new palladium(II) complexes with 1-(alkyldithiocarbonyl)imidazoles[J]. JOURNAL OF COORDINATION CHEMISTRY,2014,67(3):461-469.
APA Hou, Xueling,Li, Xiaobo,Hemit, Helimay,Aisa, Haji Akber,&Hou, XL.(2014).Synthesis, characterization, and antitumor activities of new palladium(II) complexes with 1-(alkyldithiocarbonyl)imidazoles.JOURNAL OF COORDINATION CHEMISTRY,67(3),461-469.
MLA Hou, Xueling,et al."Synthesis, characterization, and antitumor activities of new palladium(II) complexes with 1-(alkyldithiocarbonyl)imidazoles".JOURNAL OF COORDINATION CHEMISTRY 67.3(2014):461-469.
Files in This Item:
File Name/Size DocType Version Access License
Synthesis, character(233KB)期刊论文作者接受稿开放获取CC BY-NC-SAView Application Full Text
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Hou, Xueling]'s Articles
[Li, Xiaobo]'s Articles
[Hemit, Helimay]'s Articles
Baidu academic
Similar articles in Baidu academic
[Hou, Xueling]'s Articles
[Li, Xiaobo]'s Articles
[Hemit, Helimay]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Hou, Xueling]'s Articles
[Li, Xiaobo]'s Articles
[Hemit, Helimay]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: Synthesis, characterization, and antitumor activities of new palladium(II) complexes with 1-(alkyldithiocarbonyl)imidazoles .pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.