XJIPC OpenIR  > 资源化学研究室
一种控制释放药物载体的合成技术
高林; 谭中文; 田华; 向迎梅
2005-06-15
Rights Holder中国科学院新疆理化技术研究所
Date Available2013-11-27
Country中国
Subtype发明
Abstract本发明涉及一种控制释放药物载体的合成技术,首先选择单体,将两种单体通过控制单体的浓度、反应温度、采用引发剂进行诱发,通过游离基聚合或碳离子聚合或配位聚合的反应,发生共聚合反应,最后生成等规或非等规的高分子共聚物,然后将聚合物溶于水中,加入需包裹的药物成分,用酸调节溶液的pH值,包有药物的聚合物析出,分离经干燥后即可得到控制释放药物载体的制剂。用该方法制得的制剂包入药物进入人体后,在pH值低于某一值时,聚合物不溶或几乎不溶,而在pH大于某一值时,聚合物发生溶解并将所包药物释放出来,使药物在人体特定的pH环境下,将药物释放出来,充分起到药效的作用。
Application Date2002-01-19
Patent NumberZL02101964.9
Status专利权的终止
Application Number02101964.9
Document Type专利
Identifierhttp://ir.xjipc.cas.cn/handle/365002/3157
Collection资源化学研究室
Recommended Citation
GB/T 7714
高林,谭中文,田华,等. 一种控制释放药物载体的合成技术. ZL02101964.9[P]. 2005-06-15.
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