The copper borate Li2Pb2CuB4O40 has been synthesized in air by the standard solid-state reaction at temperature in the range 550-650 degrees C and the structure of Li2Pb2CuB4O10 was determined by single-crystal X-ray diffraction. Li2Pb2CuB4O10 crystallizes in the monoclinic space group C2/c (no. 15) with a=16.8419(12), b=4.7895(4), c = 13.8976(10)angstrom, and beta = 125.3620(10)degrees, V=914.22(12)angstrom(3), and Z=4, as determined by single-crystal X-ray diffraction. The Li2Pb2CuB4O10 structure exhibits isolated units of stoichiometry CuB4O10(6-) that are built from CuO4 distorted square planes and triangular BO3 groups. The IR spectroscopy and thermal analysis investigations of Li2Pb2CuB4O10 are also presented. (C) 2010 Elsevier B.V. All rights reserved.