Chemical Modification of Rupestonic Acid and Preliminarily In Vitro Antiviral Activity Against Influenza A(3) and B Viruses
Yong Jian-ping; Aisa Haji Akber; Aisa, HA
2011
发表期刊BULLETIN OF THE KOREAN CHEMICAL SOCIETY
ISSN0253-2964
卷号32期号:4页码:1293-1297
摘要To improve the biological activities of rupestonic acid, 21 new rupestonic acid fatty ester derivatives (2a-2h) and aromatic ester derivatives (2i-2u) were synthesized and preliminarily evaluated for their anti-influenza activity in vitro by the national center for drug screening of China, using the Oseltamivir and Ribavirin as reference drugs. The results showed that 21(IC50= 0.5 mu mol/L) exhibited potent anti-influenza A(3) viral activity among the synthesized compounds and was 10-fold more potent than that of the reference drug Oseltamivir (IC50 = 5.1 mu mol/L).
关键词Synthesis Rupestonic Acid Ester Derivatives Anti-influenza Virus
学科领域Chemistry
DOI10.5012/bkcs.2011.32.4.1293
收录类别SCI
WOS记录号WOS:000290366200035
引用统计
被引频次:7[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.xjipc.cas.cn/handle/365002/2783
专题省部共建新疆特有药用资源利用重点实验室
通讯作者Aisa, HA
作者单位Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Key Lab Plant Resources & Nat Prod Chem, Urumqi 830011, Peoples R China;Ningxia Med Univ, Sch Publ Hlth, Yinchuan 750004, Peoples R China
推荐引用方式
GB/T 7714
Yong Jian-ping,Aisa Haji Akber,Aisa, HA. Chemical Modification of Rupestonic Acid and Preliminarily In Vitro Antiviral Activity Against Influenza A(3) and B Viruses[J]. BULLETIN OF THE KOREAN CHEMICAL SOCIETY,2011,32(4):1293-1297.
APA Yong Jian-ping,Aisa Haji Akber,&Aisa, HA.(2011).Chemical Modification of Rupestonic Acid and Preliminarily In Vitro Antiviral Activity Against Influenza A(3) and B Viruses.BULLETIN OF THE KOREAN CHEMICAL SOCIETY,32(4),1293-1297.
MLA Yong Jian-ping,et al."Chemical Modification of Rupestonic Acid and Preliminarily In Vitro Antiviral Activity Against Influenza A(3) and B Viruses".BULLETIN OF THE KOREAN CHEMICAL SOCIETY 32.4(2011):1293-1297.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
chemical modificatio(459KB)期刊论文作者接受稿开放获取CC BY-NC-SA浏览 请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Yong Jian-ping]的文章
[Aisa Haji Akber]的文章
[Aisa, HA]的文章
百度学术
百度学术中相似的文章
[Yong Jian-ping]的文章
[Aisa Haji Akber]的文章
[Aisa, HA]的文章
必应学术
必应学术中相似的文章
[Yong Jian-ping]的文章
[Aisa Haji Akber]的文章
[Aisa, HA]的文章
相关权益政策
暂无数据
收藏/分享
文件名: chemical modification of rupestonic acid and preliminarily in vitro antiviral activity against influenza a3 and b viruses.pdf
格式: Adobe PDF
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。