chemical components and antidiabetic activity of essential oils obtained by hydrodistillation and three solvent extraction methods from carthamus tinctorius l.
Li L.; Wang Q.; Yang Y.; Wu G.; Xin X.; Aisa H. A.; Aisa, HA
2012
发表期刊ACTA CHROMATOGRAPHICA
ISSN1233-2356
卷号24期号:4页码:653-665
摘要The chemical compositions of essential oils extracted by n-hexane extract (HE), petroleum ether extract (PE), dichloromethane extract (DE), and hydrodistillation (HD) from Carthamus tinctorius L. (safflower) were analyzed by gas chromatography-mass spectrometry (GC-MS). A total of 86 compounds from four different extracts were identified, and the contents were 97.65%, 98.05%, 98.93%, and 99.68%, respectively. 6,10,14-Trimethyl-2-pentadecanone, hexadecanoic acid, methyl ester, hexadecanoic acid, 8,11-octadecadienoic acid, methyl ester, and 9,12,15-octadecatrien-1-ol were the major constituents of the extracts. The antidiabete activity was assayed in vitro by against protein tyrosine phosphatase 1B (PTP1B). The results showed that the HE exhibited the best in vitro inhibitory enzyme activity against PTP1B, which holds a good potential for treating diabetes and obesity.
关键词Carthamus Tinctorius L. (saffL.wer) Essential Oils Hydrodistillation Solvent Extract Gc-ms Antidiabete Activity
学科领域Chemistry
DOI10.1556/AChrom.24.2012.4.11
收录类别SCI
WOS记录号WOS:000311308100010
引用统计
被引频次:10[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.xjipc.cas.cn/handle/365002/2742
专题省部共建新疆特有药用资源利用重点实验室
通讯作者Aisa, HA
作者单位Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Key Lab Xinjiang Indigenous Med Plants Resource U, Urumqi 830011, Peoples R China;Xinjiang Med Univ, Sch Pharm, Urumqi 830054, Peoples R China
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Li L.,Wang Q.,Yang Y.,et al. chemical components and antidiabetic activity of essential oils obtained by hydrodistillation and three solvent extraction methods from carthamus tinctorius l.[J]. ACTA CHROMATOGRAPHICA,2012,24(4):653-665.
APA Li L..,Wang Q..,Yang Y..,Wu G..,Xin X..,...&Aisa, HA.(2012).chemical components and antidiabetic activity of essential oils obtained by hydrodistillation and three solvent extraction methods from carthamus tinctorius l..ACTA CHROMATOGRAPHICA,24(4),653-665.
MLA Li L.,et al."chemical components and antidiabetic activity of essential oils obtained by hydrodistillation and three solvent extraction methods from carthamus tinctorius l.".ACTA CHROMATOGRAPHICA 24.4(2012):653-665.
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