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鹰嘴豆有效成分B对糖尿病大鼠骨骼肌PPAR-γ基因转录水平的影响
Alternative Titlethe effect of the effective component b in chickpea on the transcription level of ppar-gamma gene in ir rats
凯赛尔·阿不都克热木; 彭晓明; 魏媛媛; 李潇; 阿吉艾克拜尔·艾萨; 帕尔哈提·克力木
2012
Source Publication时珍国医国药
ISSN1008-0805
Volume23Issue:1Pages:35-36
Other Abstract

目的探讨鹰嘴豆有效成分B对糖尿病大鼠骨骼肌PPAR-γ基因转录水平的影响。方法利用半定量RT-PCR测定给药后各组的光密度值,计算各组的PPAR-γ/β-actin值从而分析PPAR-γ基因转录水平的变化。结果鹰嘴豆有效成分B对PPAR-γ基因的转录水平具有促进作用,药物浓度在300 mg.kg-1时的效果最为明显。结论鹰嘴豆有效成分B可上调糖尿病大鼠骨骼肌PPAR-γ基因的转录。 

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Objective To investigate the effect of the effective component B in Chickpea on the transcription level of PPAR-gamma gene in IR rats. Methods Mensured light density of every group by semi-quantitative RT-PCR after using medicine,and analyzed the change of the transcription level of PPAR-gamma gene by calculating PPAR-gamma/beta-actin of every group. Results The Chickpea effective component B has effect of promoting the transcription level of PPAR-gamma gene,and its best medicine concentration is 300mg·kg~(-1). Conclusion The Chickpea effective component B can up-regulate the transcription level of PPAR-gamma gene in IR rats.

Keyword鹰嘴豆 糖尿病 过氧化物酶体增殖物激活受体gamma
Subject AreaGeneral & Internal Medicine (Provided By Thomson Reuters)
Indexed ByCSCD
CSCD IDCSCD:4444384
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Document Type期刊论文
Identifierhttp://ir.xjipc.cas.cn/handle/365002/2598
Collection资源化学研究室
Affiliation新疆医科大学药学院;新疆维吾尔医药研究所;中国科学院新疆理化技术研究所
Recommended Citation
GB/T 7714
凯赛尔·阿不都克热木,彭晓明,魏媛媛,等. 鹰嘴豆有效成分B对糖尿病大鼠骨骼肌PPAR-γ基因转录水平的影响[J]. 时珍国医国药,2012,23(1):35-36.
APA 凯赛尔·阿不都克热木,彭晓明,魏媛媛,李潇,阿吉艾克拜尔·艾萨,&帕尔哈提·克力木.(2012).鹰嘴豆有效成分B对糖尿病大鼠骨骼肌PPAR-γ基因转录水平的影响.时珍国医国药,23(1),35-36.
MLA 凯赛尔·阿不都克热木,et al."鹰嘴豆有效成分B对糖尿病大鼠骨骼肌PPAR-γ基因转录水平的影响".时珍国医国药 23.1(2012):35-36.
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