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ANTIDIABETES PROPERTIES OF n-HEXANE AND PETROLEUM ETHER EXTRACTS FROM SEEDS OF NIGELLA GLANDULIFERA FREYN
Xin Xuelei; Wang Qi; Aisa Haji Akber; Wang Hanqing; Aisa, HA
2010
发表期刊Journal of Food Biochemistry
ISSN1458884
卷号34期号:4页码:811-824
摘要Nigella glandulifera Freyn, an annual plant species of the family Ranunculaceae, served as a traditional Uigur medicine and food. Many researchers have reported that Nigella sativa L., which is the same genus with it, has an antidiabetic effect, the seeds oil was an activity component used as a kind of function food. In the present study, the difference of oil extract between n-hexane and petroleum ether respectively from the seeds of Nigella glandulifera Freyn were analyzed by gas chromatography-mass spectrometry, all of them can inhibit protein tyrosine phosphatase 1B (PTP1B) with half maximal inhibitory concentration values of 33.15 ± 0.77 and 18.50 ± 0.52 μg/mL, respectively. They have different binding sites with PTP1B. Lastly, inhibited ability of PTP1B and that of TCPTP were compared; all of them have shown some selectivity.
学科领域Biochemistry & Molecular Biology ; Food Science & Technology
DOI10.1111/j.1745-4514.2009.00318.x
收录类别SCI
WOS记录号WOS:000280643000008
引用统计
被引频次:6[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.xjipc.cas.cn/handle/365002/1823
专题资源化学研究室
通讯作者Aisa, HA
作者单位Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China;Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Urumqi 830011, Peoples R China;Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China;Chinese Acad Sci, Drug Discovery & Design Ctr, State Key Lab Drug Res, Shanghai Inst Biol Sci, Shanghai 201203, Peoples R China
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Xin Xuelei,Wang Qi,Aisa Haji Akber,et al. ANTIDIABETES PROPERTIES OF n-HEXANE AND PETROLEUM ETHER EXTRACTS FROM SEEDS OF NIGELLA GLANDULIFERA FREYN[J]. Journal of Food Biochemistry,2010,34(4):811-824.
APA Xin Xuelei,Wang Qi,Aisa Haji Akber,Wang Hanqing,&Aisa, HA.(2010).ANTIDIABETES PROPERTIES OF n-HEXANE AND PETROLEUM ETHER EXTRACTS FROM SEEDS OF NIGELLA GLANDULIFERA FREYN.Journal of Food Biochemistry,34(4),811-824.
MLA Xin Xuelei,et al."ANTIDIABETES PROPERTIES OF n-HEXANE AND PETROLEUM ETHER EXTRACTS FROM SEEDS OF NIGELLA GLANDULIFERA FREYN".Journal of Food Biochemistry 34.4(2010):811-824.
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