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学科主题: Biochemistry & Molecular Biology ; Food Science & Technology
题名: ANTIDIABETES PROPERTIES OF n-HEXANE AND PETROLEUM ETHER EXTRACTS FROM SEEDS OF NIGELLA GLANDULIFERA FREYN
作者: Xin Xuelei; Wang Qi; Aisa Haji Akber; Wang Hanqing
通讯作者: Aisa, HA
刊名: Journal of Food Biochemistry
发表日期: 2010
DOI: 10.1111/j.1745-4514.2009.00318.x
卷: 34, 期:4, 页:811-824
收录类别: SCI
摘要: Nigella glandulifera Freyn, an annual plant species of the family Ranunculaceae, served as a traditional Uigur medicine and food. Many researchers have reported that Nigella sativa L., which is the same genus with it, has an antidiabetic effect, the seeds oil was an activity component used as a kind of function food. In the present study, the difference of oil extract between n-hexane and petroleum ether respectively from the seeds of Nigella glandulifera Freyn were analyzed by gas chromatography-mass spectrometry, all of them can inhibit protein tyrosine phosphatase 1B (PTP1B) with half maximal inhibitory concentration values of 33.15 ± 0.77 and 18.50 ± 0.52 μg/mL, respectively. They have different binding sites with PTP1B. Lastly, inhibited ability of PTP1B and that of TCPTP were compared; all of them have shown some selectivity.
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内容类型: 期刊论文
URI标识: http://ir.xjipc.cas.cn/handle/365002/1823
Appears in Collections:资源化学研究室_期刊论文

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作者单位: Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China;Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Urumqi 830011, Peoples R China;Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China;Chinese Acad Sci, Drug Discovery & Design Ctr, State Key Lab Drug Res, Shanghai Inst Biol Sci, Shanghai 201203, Peoples R China

Recommended Citation:
Xin Xuelei,Wang Qi,Aisa Haji Akber,et al. ANTIDIABETES PROPERTIES OF n-HEXANE AND PETROLEUM ETHER EXTRACTS FROM SEEDS OF NIGELLA GLANDULIFERA FREYN[J]. Journal of Food Biochemistry,2010,34(4):811-824.
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文件名: antidiabetes properties of n-hexane and petroleum ether extracts from seeds of nigella glandulifera freyn.pdf
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