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学科主题: Pharmacology & Pharmacy
题名: Laevigatbenzoate from Croton laevigatus Vahl.
作者: Zou Guo-An; Zhang Hong-Wu; Aisa Haji Akber; Yang Jun-Shan; Peng Chao-Zhong; Zou Zhong-Mei
关键词: Croton laevigatus Vahl. ; Euphorbiaceae ; Diterpenoid ; Laevigatbenzoate ; Cytotoxicity
刊名: JOURNAL OF NATURAL MEDICINES
发表日期: 2011
DOI: 10.1007/s11418-010-0503-9
卷: 65, 期:2, 页:391-394
收录类别: SCI
资助者: Major Project of Chinese National Programs for Severe Infectious Diseases;National Natural Science Foundation of China;National S&T Major Special Project on Major New Drug Innovation
摘要: A new trans-clerodane diterpenoid, laevigatbenzoate (1), was isolated from the leaves of Croton laevigatus Vahl. Its structure was established on the basis of spectroscopic analysis, and the absolute configuration was determined by application of the CD excitation chirality method. This compound showed weak cytotoxicity against HeLa cells, with an IC(50) value of 45.4 mu M.
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内容类型: 期刊论文
URI标识: http://ir.xjipc.cas.cn/handle/365002/1667
Appears in Collections:资源化学研究室_期刊论文

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作者单位: Chinese Acad Med Sci, Inst Med Plant Dev, Beijing 100193, Peoples R China;Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Urumqi 830011, Peoples R China

Recommended Citation:
Zou Guo-An,Zhang Hong-Wu,Aisa Haji Akber,et al. Laevigatbenzoate from Croton laevigatus Vahl.[J]. JOURNAL OF NATURAL MEDICINES,2011,65(2):391-394.
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文件名: laevigatbenzoate from croton laevigatus vahl..pdf
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