中国科学院新疆理化技术研究所机构知识库
Advanced  
XJIPC OpenIR  > 省部共建新疆特有药用资源利用重点实验室  > 期刊论文
学科主题: Pharmacology & Pharmacy ; Chemistry
题名: Chemical transformations of mackinazolinone and its derivatives
作者: Nasrullaev A. O.; Turdibaev Zh E.; Elmuradov B. Zh; Yili A.; Aisa H. A.; Shakhidoyatov Kh M.
关键词: mackinazolinone ; mackinazolinthione ; nucleophilic substitution ; electrophilic addition
刊名: CHEMISTRY OF NATURAL COMPOUNDS
发表日期: 2012
DOI: 10.1007/s10600-012-0331-0
卷: 48, 期:4, 页:638-642
收录类别: SCI
资助者: RU TsNT
摘要: The thioanalog of mackinazolinone (2,3,4,10-tetrahydro-1 H-pyrido2,1-bquinazolin-10-one) was synthesized for the first time by reacting it with P2S5. The thioanalog was reacted with aromatic aldehydes and Vilsmeier- Haack reagent (DMF + POCl3) to produce 4-arylidene- and -hydroxymethylidenemackinazolinthiones, respectively. The reactions of 4-hydroxymethylidenemackinazolinone with isomeric aminophenols and aminobenzoic acids and of hydroxymethylidenemackinazolinthione with thionylchloride were studied. Subsequent reaction of the obtained 4-chloromethylidene derivative with sodium hydroselenide was synthesized a new Se-containing derivative of mackinazolinone. It was shown that 4-formylmackinazolinthione existed in the enol form whereas 4-formylmackinazolinone existed as the enaminoaldehyde tautomer.
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.xjipc.cas.cn/handle/365002/1610
Appears in Collections:新疆维吾尔自治区植物资源化学重点实验室 _期刊论文

Files in This Item:
File Name/ File Size Content Type Version Access License
chemical transformations of mackinazolinone and its derivatives.pdf(77KB)期刊论文作者接受稿开放获取View 联系获取全文

作者单位: Uzbek Acad Sci, S Yu Yunusov Inst Chem Plant Subst, Tashkent 700135, Uzbekistan;Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Key Lab Xinjiang Indigenous Med Plants Resource U, Urumqi 830011, Peoples R China

Recommended Citation:
Nasrullaev A. O.,Turdibaev Zh E.,Elmuradov B. Zh,et al. Chemical transformations of mackinazolinone and its derivatives[J]. CHEMISTRY OF NATURAL COMPOUNDS,2012,48(4):638-642.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Nasrullaev A. O.]'s Articles
[Turdibaev Zh E.]'s Articles
[Elmuradov B. Zh]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Nasrullaev A. O.]‘s Articles
[Turdibaev Zh E.]‘s Articles
[Elmuradov B. Zh]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
文件名: chemical transformations of mackinazolinone and its derivatives.pdf
格式: Adobe PDF
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Powered by CSpace