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Alternative TitleEffects of total saponins from Cicer arietinum L.on blood glucose and pancreatic pathology of type 2 diabetes mellitus rats
凯赛尔·阿不都克热木; 李治建; 李潇; 阿吉艾克拜尔·艾萨; 闫冬; 帕尔哈提·克里木
Source Publication中药药理与临床


Other Abstract

Objective:To study the effects of total saponins from Cicer arietinum L.(TSCA)on blood glucose and pancreatic pathology of type 2 diabetes mellitus(T2DM)rats.Methods:Established T2DM rats model with high calorie feeding and injection of STZ(45 mg/kg).T2DM rats were randomly assigned to model group and TSCA treat group.These two groups were treated with irrigate stomach.,Detected fasting glucose(FPG)and observed the pancreatic pathology 2 weeks after treating with TSCA.Result:Compared with model group,total saponins from Cicer arietinum L.can effectively reduce blood glucose in Type 2 diabetes mellitus rats,and can repair the damaged pancreatic pathology.Conclusion:The result suggests that TSCA could be used to reduce FPG and to repair the damaged pancreatic pathology of T2DM rats.

KeywordTotal Saponins From Cicer Arietinum(Tsca) Type 2 Diabetes Mellitus Glucose Pancreatic Pathological Structure
Subject AreaGeneral & Internal Medicine (Provided By Thomson Reuters)
Indexed ByCSCD
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Document Type期刊论文
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GB/T 7714
凯赛尔·阿不都克热木,李治建,李潇,等. 鹰嘴豆总皂苷对2型糖尿病大鼠血糖及胰腺病理结构的影响[J]. 中药药理与临床,2011,27(3):47-49.
APA 凯赛尔·阿不都克热木,李治建,李潇,阿吉艾克拜尔·艾萨,闫冬,&帕尔哈提·克里木.(2011).鹰嘴豆总皂苷对2型糖尿病大鼠血糖及胰腺病理结构的影响.中药药理与临床,27(3),47-49.
MLA 凯赛尔·阿不都克热木,et al."鹰嘴豆总皂苷对2型糖尿病大鼠血糖及胰腺病理结构的影响".中药药理与临床 27.3(2011):47-49.
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